TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 40nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 60nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 83nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 425nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 565nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetHistamine H3 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataKi: 1.62E+3nMAssay Description:Displacement of [3H]-N-alpha-methylhistamine from human H3 receptor expressed in HEK293 cell membranes incubated for 60 mins by scintillation countin...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of GSK3beta (unknown origin) pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured afte...More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Alma Mater Studiorum-University of Bologna
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of GSK3beta (unknown origin) pre-incubated for 30 mins followed by ULight-GS (Ser641/pSer657) peptide substrate addition and measured afte...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO-K1 cells co-expressing G protein alpha16 assessed as inhibition of histamine-induced calciu...More data for this Ligand-Target Pair
TargetHistamine H4 receptor(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human H4 receptor expressed in CHO-K1 cells co-expressing G protein alpha16 assessed as inhibition of histamine-induced calciu...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of KCl-induced cytosolic voltage gated calcium channel opening in human SH-SY5Y cells by Fluo-4 AM dye based fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of BuChE in human plasma using butyrylthiocholine iodide substrate by Ellman's protocol based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.22E+3nMAssay Description:Inhibition of BuChE in human plasma using butyrylthiocholine iodide substrate by Ellman's protocol based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 7.83E+3nMAssay Description:Inhibition of BuChE in human plasma using butyrylthiocholine iodide substrate by Ellman's protocol based assayMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1F(Homo sapiens (Human))
Universidad Aut£noma de Madrid
Curated by ChEMBL
Universidad Aut£noma de Madrid
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of K+-induced voltage gated calcium channel opening in human SH-SY5Y cells assessed as decrease in Ca2+ level after 10 mins by Fluo-4 dye-...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1C/alpha-1D/alpha-1F/alpha-1S(Homo sapiens (Human))
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Universit£ Bourgogne Franche-Comt£
Curated by ChEMBL
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of voltage-dependent L-type calcium channel in 70 mM K+-induced human SH-SY5Y cells assessed as blocking of depolarization-induced Ca2+ up...More data for this Ligand-Target Pair
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