Affinity DataKi: 6.40E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C by amplex red assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+3nMAssay Description:Inhibition of Bacillus cereus phospholipase C using L-alpha-phosphatidylcholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataKi: 7.10E+4nMAssay Description:Inhibition of Bacillus cereus PC-phospholipase C using phosphoryl-choline as substrate by molybdenum blue dye based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2NK3K2FPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2NK3K2FPubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 23nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 63nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 232nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 450nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured after 20 mins by electrophoresis...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 720nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 810nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 980nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant Bacillus cereus N-terminal His6-tagged full length PC-PLC 3C Protease cleavage site expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of recombinant Bacillus cereus N-terminal His6-tagged full length PC-PLC 3C Protease cleavage site expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 3.69E+3nMAssay Description:Inhibition of recombinant Bacillus cereus N-terminal His6-tagged full length PC-PLC 3C Protease cleavage site expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-([32P]-aac gtc agg gtc ttc c-tyrosine)-3' as substrate measured after 5 mins by electrophore...More data for this Ligand-Target Pair
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant Bacillus cereus N-terminal His6-tagged full length PC-PLC 3C Protease cleavage site expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
TargetTyrosyl-DNA phosphodiesterase 1(Homo sapiens (Human))
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Siberian Branch of the Russian Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 6.73E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-aac gtc agg gtc ttc c-BHQ1)-3' as substrate measured every 55 secs for 8 mins by fl...More data for this Ligand-Target Pair
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 8.08E+3nMAssay Description:Inhibition of recombinant Bacillus cereus N-terminal His6-tagged full length PC-PLC 3C Protease cleavage site expressed in Escherichia coli BL21(DE3)...More data for this Ligand-Target Pair