TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.30nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 3.5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Activity at GR assessed as ability to antagonize dexamethasone-induced MMTV luciferase reporter gene transactivation in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 4.90nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5.60nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 5.80nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 6.40nMAssay Description:Affinity for human glucocorticoid receptorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 7.90nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 8.10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 8.5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 9.5nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 11.7nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...More data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Agonist activity at GR assessed as NF-kappaB-mediated transrepression of secreted placental alkaline phosphatase gene in human A549 cellsChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
TargetGlucocorticoid receptor(Homo sapiens (Human))
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
GlaxoSmithKline Medicines Research Centre
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of fluorescent-labeled Dexamethasone binding to GRChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced IL-6 secretion incubated for 18 to 24 hrs by MSD assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Displacement of Alexa Fluor 647 labelled ligand from recombinant human N-terminal 6His-tagged BRD4-BD1 Y390A mutant (1 to 477 residue) expressed in E...More data for this Ligand-Target Pair