Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.10nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 6.70nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 40nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 41nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 49nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 58nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 59nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 73nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 130nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 260nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 270nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 460nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.50E+3nMAssay Description:Displacement of [3H]UR-MK114 from NPY1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of NG-([2,3-3H]propionyl)-BIBP-3226 from NPY Y1 receptor in human SK-N-MC cellsMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 119nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 172nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 179nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 183nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 193nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Inhibition of ABCB1 overexpressed in human KBv1 cells by flow cytometric-based calcein-AM efflux assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 223nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 225nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 250nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 317nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 508nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 526nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 552nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 632nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 858nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 916nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 977nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
University of Regensburg
Curated by ChEMBL
University of Regensburg
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABCC2 overexpressed in MDCK cells at 100 uM by flow cytometric-based chloromethylfluorescein-diacetate accumulation assayMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of ABCB1 expressed in Kb-V1 cells after 10 mins by calcein-AM assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of ABCG2 overexpressed in human MCF7/Topo cells by flow cytometric-based mitoxantrone efflux assayMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
Universidad Nacional de Colombia
Curated by ChEMBL
Universidad Nacional de Colombia
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of ABCG2 expressed in human MCF7/Topo cells by Hoechst microplate assayMore data for this Ligand-Target Pair
![](/img/powered_by_small.gif)