Affinity DataIC50: 200nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 251nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of human JNK2alpha2More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of human JNK2alpha2More data for this Ligand-Target Pair
Affinity DataIC50: 398nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2TB1840PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2TB1840PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 501nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human truncated JNK3More data for this Ligand-Target Pair
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human JNK2alpha2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VegFr2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cFmsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PLK1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFRMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Alk5More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ErbB2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length ERK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
GlaxoSmithKline R&D
Curated by ChEMBL
GlaxoSmithKline R&D
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cFmsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant full length JNK1alpha1More data for this Ligand-Target Pair