TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataKi: 1.10E+3nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataKi: 5.30E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataKi: 8.80E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataKi: 9.00E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
St. Jude Children's Research Hospital
Curated by ChEMBL
St. Jude Children's Research Hospital
Curated by ChEMBL
Affinity DataIC50: 0.780nMAssay Description:Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human GST-tagged IGF1R by trans-phosphorylation assayMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of IGF1R in human MCF7 cells by western blot analysisMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in baculovirus-infected Sf21 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Mus musculus)
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of IGF1R in IGF1-stimulated human MCF7 cells by western blot analysisMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 650nMAssay Description:Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.03E+3nMAssay Description:Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition for IGF1R-induced S6 ribosomal protein phosphorylation in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant IRKMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Antiproliferative activity against human NPM-ALK positive anaplastic large cell lymphoma karpas299 cell lineMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibitory activity against IRKMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against ALKMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 3.80E+3nMAssay Description:Antiproliferative activity against human BCR-ABL positive chronic myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
ChemBridge Research Laboratories and ChemBridge Corporation
Curated by ChEMBL
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against Flt3More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
St. Jude Children's Research Hospital
Curated by ChEMBL
St. Jude Children's Research Hospital
Curated by ChEMBL
Affinity DataIC50: 4.01E+3nMAssay Description:Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 minsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant IGFR1More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair