TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 49nMAssay Description:Inhibition of human GST-tagged IGF1R by trans-phosphorylation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of insulin receptorMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of IGF1R in human MCF7 cells by western blot analysisMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of GST-tagged human IGF1R expressed in baculovirus-infected Sf21 cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Mus musculus)
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Inhibition of IGF1R by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 300nMAssay Description:Inhibition of IGF1R in IGF1-stimulated human MCF7 cells by western blot analysisMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 340nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of IGF1R in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of insulin receptor by cell based assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition for IGF1R-induced S6 ribosomal protein phosphorylation in growth factor-stimulated NHDFMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of c-KITMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Mus musculus)
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Mus musculus)
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of IGF1R-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR-ABL p210More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BCR-ABL p210More data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER2More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HER1More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of IGF1R autophosphorylation in human MCF7 cells by ELISAMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of insulin receptor-mediated proliferation of mouse NIH/3T3 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
University of South Florida
Curated by ChEMBL
University of South Florida
Curated by ChEMBL
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair