TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.0800nMAssay Description:Inhibition of human P2Y14RMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.210nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.220nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
Affinity DataKi: 0.340nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from rat A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation prox...More data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [125I]I-AB-MECA from human adenosine A3 receptor expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.370nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
TargetP2Y purinoceptor 14(Homo sapiens (Human))
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
National Institute of Diabetes and Digestive and Kidney Diseases
Curated by ChEMBL
Affinity DataKi: 0.430nMAssay Description:Antagonist activity at human P2Y14 expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP accumulation incubated for 15 ...More data for this Ligand-Target Pair
Affinity DataKi: 0.436nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.441nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.450nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.511nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.626nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.650nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.673nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.680nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.710nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.75nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.830nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 0.848nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.894nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 0.896nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
Affinity DataKi: 0.960nMAssay Description:Displacement of [3H]HMRS7799 from human adenosine A3 receptor expressed in HEK293 cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyluronamide from human adrenergic A3 receptor expressed in CHO cell membranes asses...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from mouse A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]N6-R-phenylisopropyladenosine from human A1A adenosine receptor expressed in CHO cell membranes after 60 mins by scintillation pr...More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 1.30nMAssay Description:Inhibition of human soluble CD73 assessed as inhibition constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Binding affinity to human A3AR assessed as inhibitor constantMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]HEMADO from human adenosine A3 receptor expressed in CHO cell membranes after 3 hrs by micro beta scintillation counting methodMore data for this Ligand-Target Pair