Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Mahidol University
Curated by ChEMBL
Mahidol University
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of human HMGR catalytic domain using 800 uM HMG-CoA as substrate measured every 20 secs for 10 minsMore data for this Ligand-Target Pair
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Prince of Songkla University
Curated by ChEMBL
Prince of Songkla University
Curated by ChEMBL
Affinity DataIC50: 5.86E+4nMAssay Description:Inhibition of CFTR-mediated forskolin-induced chloride secretion in human T84 cells after 15 mins by short-circuit current analysisMore data for this Ligand-Target Pair
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Homo sapiens (Human))
Mahidol University
Curated by ChEMBL
Mahidol University
Curated by ChEMBL
Affinity DataIC50: 3.87E+5nMAssay Description:Inhibition of human HMGR catalytic domain using 800 uM HMG-CoA as substrate measured every 20 secs for 10 minsMore data for this Ligand-Target Pair