Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 36nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 37nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 81nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 85nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 112nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 121nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 127nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
Affinity DataIC50: 129nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 145nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 155nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 212nMAssay Description:Inhibition of HDAC in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 221nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 248nMAssay Description:Antagonist activity at Gal4 DBD-fused human ERalpha LBD expressed in HEK293T cells assessed as inhibition of estradiol-induced transcriptional activa...More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of HDAC6 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 369nMAssay Description:Inhibition of HDAC1 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 524nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 567nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant HDAC6 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2B56NN3PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2B56NN3PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of HDAC8 in human HeLa cells using Fluor-de-Lys as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar
In DepthDetails
Article
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
BindingDB Entry DOI: 10.7270/Q2XP77W3PubMedDrugBank
MMDB
PDB
3D Structure (crystal)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human recombinant HDAC1 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant HDAC8 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair