Compile Data Set for Download or QSAR
Found 253 of ic50 for UniProtKB: P05556
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199337(CHEMBL3962660 | US10131658, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199337(CHEMBL3962660 | US10131658, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199345(CHEMBL3893700 | US10131658, Compound 201)copy SMILEScopy InChI
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199345(CHEMBL3893700 | US10131658, Compound 201)copy SMILEScopy InChI
Affinity DataIC50: 0.0631nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50554031(CHEMBL4749110)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50554030(CHEMBL4756339)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50554033(CHEMBL4794201)copy SMILES
Affinity DataIC50: 0.100nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199411(CHEMBL3951678 | US10131658, Compound 87)copy SMILEScopy InChI
Affinity DataIC50: 0.126nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199411(CHEMBL3951678 | US10131658, Compound 87)copy SMILEScopy InChI
Affinity DataIC50: 0.130nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)copy SMILEScopy InChI
Affinity DataIC50: 0.140nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199196(CHEMBL3905970)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199196(CHEMBL3905970)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199399(CHEMBL3909977 | US10131658, Compound 212)copy SMILEScopy InChI
Affinity DataIC50: 0.25nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199399(CHEMBL3909977 | US10131658, Compound 212)copy SMILEScopy InChI
Affinity DataIC50: 0.251nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50554032(CHEMBL4741135)copy SMILES
Affinity DataIC50: 0.300nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) by solid phase binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199398(CHEMBL3952235 | US10131658, Compound 211)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199197(CHEMBL3923968 | US10131658, Compound 11)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199398(CHEMBL3952235 | US10131658, Compound 211)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199197(CHEMBL3923968 | US10131658, Compound 11)copy SMILEScopy InChI
Affinity DataIC50: 0.316nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50141334(3-[4-(3-Guanidino-benzoylamino)-phenyl]-2-isopropo...)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Binding affinity towards alpha V-beta5 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HXSPubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199338(CHEMBL3932911)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199335(CHEMBL3899812)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199195(CHEMBL3892042 | US10131658, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199338(CHEMBL3932911)copy SMILEScopy InChI
Affinity DataIC50: 0.501nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199335(CHEMBL3899812)copy SMILEScopy InChI
Affinity DataIC50: 0.501nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199195(CHEMBL3892042 | US10131658, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 0.630nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199195(CHEMBL3892042 | US10131658, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 0.631nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50141324(2-Isopropoxycarbonylamino-3-{2-methoxy-4-[3-(1,4,5...)copy SMILEScopy InChI
Affinity DataIC50: 0.680nMAssay Description:Binding affinity towards alpha IIb/beta3 integrin by solid-phase receptor binding assay (SPRA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HXSPubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM472679(US10836720, HIJ-1017)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM472699(US10836720, HIJ-1483)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM472684(US10836720, HIJ-1018)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of alphavbeta1 integrin (unknown origin) expressed in CHO cells assessed as inhibition of cell adhesion to fibronectin incubated for 60 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25Q50R5PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)copy SMILEScopy InChI
Affinity DataIC50: 1nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50141355(3-[4-(3-Guanidino-benzoylamino)-2-methoxy-phenyl]-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Binding affinity towards alpha V/beta3 receptor by solid-phase receptor binding assays (SPRA)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4HXSPubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Antagonist activity at alphavbeta1 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XW8PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50497714(Glpg-0187 | Glpg0187)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ligand binding to integrin alphavbeta1 (unknown origin) expressed in baculovirus expression system after 2 hrs by solid-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KQHPubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50209461((3S)-3-(3-bromo-5-chloro-2-hydroxyphenyl)-3-(2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Antagonist activity at alphavbeta1 integrin receptor in HEK293 cells after 4 hrs using p-nitrophenyl phosphate by colorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XW8PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50497716(CHEMBL3319237)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Antagonist activity at alphavbeta1 integrin receptor (unknown origin) by cell-free ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0XW8PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50497716(CHEMBL3319237)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human fibronectin binding to human integrin alphavbeta1 after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75KQHPubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199339(CHEMBL3914945 | US10131658, Compound 60)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 5 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24M96KKUS Patent
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199407(CHEMBL3902668 | US10131658, Compound 202)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199339(CHEMBL3914945 | US10131658, Compound 60)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
TargetIntegrin alpha-V/beta-1(Homo sapiens (Human))
University of California-San Francisco

Curated by ChEMBL
LigandPNGBDBM50199333(CHEMBL3942926 | US10131658, Compound 61)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of integrin alphaVbeta1 (unknown origin)-mediated CHO cell adhesion to fibronectin preincubated for 15 to 30 mins followed by 60 min incub...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP76X4PubMed
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