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Compile Data Set for Download or QSAR
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Target
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human))
Vernalis (R&D) Ltd
Ligand
BDBM17144
(2-imino-thiazolidin-4-one analog, 6 | 4-(5-{[(5Z)-...)
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Affinity Data
IC50: 120nM
pH: 7.5 T: 2°C
Assay Description:
In vitro kinase assay using purified CDK2/Cyclin A was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP...
More data for this Ligand-Target Pair
Target Info
PDB
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NCI pathway
Reactome pathway
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Ligand Info
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In Depth
Details
Article
BindingDB Entry DOI:
10.7270/Q28G8HZQ
PubMed
DrugBank
PDB
3D Structure (crystal)