Affinity DataIC50: 0.520nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.600nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.860nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:In vitro Growth factor receptor bound protein 2-binding affinity of the compound was determined in in surface plasmon resonance (SPR) methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 1.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.62nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 1.80nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity in extracellular ELISA-based assay for Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.20nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.20nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of isolated thymidylate synthase partially purified from L1210 mouse leukemia cellsMore data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.40nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.5nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.60nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.60nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.60nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.70nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.70nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.70nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.70nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.80nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.80nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.90nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.90nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.90nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.90nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 2.90nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 3nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD
US Patent
Affinity DataIC50: 3nMAssay Description:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 correspond...More data for this Ligand-Target Pair