Compile Data Set for Download or QSAR
Found 7 with your filter
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50155926(CHEMBL3183703)copy SMILEScopy InChI
Affinity DataIC50: 7.5nMAssay Description:Inhibition of NLRP3 inflammasome activation in LPS-stimulated mouse BMDM assessed as reduction in NLRP3 inflammasome-induced IL-1beta production prei...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Xenome Ltd.

Curated by ChEMBL
LigandPNGBDBM50415695(CHEMBL1076360)copy SMILEScopy InChI
Affinity DataIC50: 182nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8G45PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199870(CHEMBL3904593)copy SMILEScopy InChI
Affinity DataIC50: 232nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199858(CHEMBL3956814)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199871(CHEMBL3920126)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199869(CHEMBL3929254)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The University of Queensland

Curated by ChEMBL
LigandPNGBDBM50199868(CHEMBL3906283)copy SMILEScopy InChI
Affinity DataIC50: 6.35E+3nMAssay Description:Inhibition of NLRP3 inflammasome in LPS-stimulated human monocyte derived macrophages assessed as reduction in NLRP3 inflammasome-induced IL-1beta pr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD7XKVPubMed