BindingDB PrimarySearch_ki

Found 235 with your filter

Orexin receptor type 2(Rattus norvegicus (Rat))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50417257(SB-649868)copy SMILEScopy InChI

Ki: 0.0776nMAssay Description:Antagonist activity at recombinant rat OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

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BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

Orexin/Hypocretin receptor type 1(Rattus norvegicus (Rat))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50417257(SB-649868)copy SMILEScopy InChI

Ki: 0.117nMAssay Description:Antagonist activity at recombinant rat OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

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BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

Orexin/Hypocretin receptor type 1(Homo sapiens (Human))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50419142(CHEMBL1830963)copy SMILEScopy InChI

Ki: 0.126nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413086(CHEMBL484260)copy SMILEScopy InChI

Ki: 0.126nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Orexin/Hypocretin receptor type 1(Homo sapiens (Human))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50419136(CHEMBL1830961)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413083(CHEMBL484059)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Displacement of [3H]citalopram from human SerT expressed pig LLCPK cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413084(CHEMBL521506)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413078(CHEMBL491839)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Histamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50002087(4-(1-Methyl-piperidin-4-ylidene)-4,9-dihydro-1-thi...)copy SMILEScopy InChI

Ki: 0.158nMAssay Description:Antagonist activity against human histamine H1 receptor expressed in CHO cells by FLIPR assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

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Details Article
BindingDB Entry DOI: 10.7270/Q2FQ9WWQPubMed DrugBank

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413085(CHEMBL485491)copy SMILEScopy InChI

Ki: 0.200nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413087(CHEMBL497980)copy SMILEScopy InChI

Ki: 0.200nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413075(CHEMBL489394)copy SMILEScopy InChI

Ki: 0.200nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI

Ki: 0.200nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413079(CHEMBL444398)copy SMILEScopy InChI

Ki: 0.200nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Orexin receptor type 2(Homo sapiens (Human))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50419142(CHEMBL1830963)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413081(CHEMBL523095)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413082(CHEMBL490211)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50412441(CHEMBL490417 | SB-744185)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413074(CHEMBL496317)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413074(CHEMBL496317)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413073(CHEMBL496520)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413068(CHEMBL497979)copy SMILEScopy InChI

Ki: 0.251nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413083(CHEMBL484059)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413068(CHEMBL497979)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Orexin/Hypocretin receptor type 1(Homo sapiens (Human))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50417257(SB-649868)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Antagonist activity at recombinant human OX1R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase MCE
PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413084(CHEMBL521506)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413070(CHEMBL495705)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413080(CHEMBL489195)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413077(CHEMBL522257)copy SMILEScopy InChI

Ki: 0.316nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Orexin receptor type 2(Homo sapiens (Human))
GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL

PNG

BDBM50417257(SB-649868)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Antagonist activity at recombinant human OX2R expressed in CHO cells by FLIPR calcium based functional assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Purchase MCE
PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q29K4CGMPubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413079(CHEMBL444398)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413077(CHEMBL522257)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413076(CHEMBL489393)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413086(CHEMBL484260)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Sodium-dependent serotonin transporter(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413072(CHEMBL495703)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]citalopram from human SerT expressed pig LLCPK cellsMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413073(CHEMBL496520)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413080(CHEMBL489195)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413073(CHEMBL496520)copy SMILEScopy InChI

Ki: 0.398nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413084(CHEMBL521506)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1D(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413071(CHEMBL521873)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]5HT from human 5HT1D receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413077(CHEMBL522257)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413087(CHEMBL497980)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413076(CHEMBL489393)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413078(CHEMBL491839)copy SMILEScopy InChI

Ki: 0.501nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413080(CHEMBL489195)copy SMILEScopy InChI

Ki: 0.631nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413083(CHEMBL484059)copy SMILEScopy InChI

Ki: 0.631nMAssay Description:Displacement of [3H]WAY-100635 from human 5HT1A receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413078(CHEMBL491839)copy SMILEScopy InChI

Ki: 0.631nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

5-hydroxytryptamine receptor 1B(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50413086(CHEMBL484260)copy SMILEScopy InChI

Ki: 0.631nMAssay Description:Displacement of [3H]5HT from human 5HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q2BR8TC6PubMed

Histamine H1 receptor(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL

PNG

BDBM50416668(CHEMBL1222552)copy SMILEScopy InChI

Ki: 0.631nMAssay Description:Antagonist activity at human recombinant histamine H1 receptor expressed in CHO cells by FLPR assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article
BindingDB Entry DOI: 10.7270/Q20R9QNTPubMed

Displayed 1 to 50 (of 235 total ) | Next | Last >>

Targets 29 ▿
- Peroxisome proliferator-activated receptor gamma 154
- Leucine-rich repeat serine/threonine-protein kinase 2 129
- Histamine H1 receptor 61
- Translocator protein 27
- Prostaglandin E2 receptor EP4 subtype 26
- Neuropeptide Y receptor type 1 23
- Sodium-dependent serotonin transporter 21
- 5-hydroxytryptamine receptor 1B 21
- 5-hydroxytryptamine receptor 1A 21
- 5-hydroxytryptamine receptor 1D 21
- Potassium voltage-gated channel subfamily H member 2 19
- Nuclear receptor ROR-gamma 19
- Cytochrome P450 3A4 18
- Orexin receptor type 2 16
- 5-hydroxytryptamine receptor 2C 16
- 5-hydroxytryptamine receptor 2B 16
- 5-hydroxytryptamine receptor 2A 16
- Orexin/Hypocretin receptor type 1 16
- Sialidase-3 12
- Cytochrome P450 1A2 8
- Cytochrome P450 2C9 8
- Cytochrome P450 2C19 8
- Cytochrome P450 2D6 8
- Prostaglandin E2 receptor EP2 subtype 5
- Nuclear receptor subfamily 1 group I member 2 3
- Solute carrier organic anion transporter family member 1B1 3
- Alpha-1B adrenergic receptor 1
- Alpha-1A adrenergic receptor 1
- SRSF protein kinase 3 1
- ...
Publications 14 ▿
- US Patent US10173996 (2019) 154
- J Med Chem 53: 7778-95 (2010) 88
- Bioorg Med Chem Lett 18: 5653-6 (2008) 84
- Bioorg Med Chem Lett 20: 5069-73 (2010) 66
- Bioorg Med Chem Lett 29: 212-215 (2019) 38
- Bioorg Med Chem Lett 27: 4034-4038 (2017) 36
- Bioorg Med Chem Lett 21: 5562-7 (2011) 32
- J Med Chem 54: 7165-75 (2011) 27
- Bioorg Med Chem Lett 17: 1043-6 (2007) 23
- US Patent US10975081 (2021) 18
- US Patent US9181279 (2015) 16
- J Med Chem 53: 8228-8240 (2010) 16
- Bioorg Med Chem Lett 21: 6336-40 (2011) 15
- Bioorg Med Chem Lett 23: 2653-8 (2013) 4
Institutions 11 ▿
- [GlaxoSmithKline] 238
- [Celgene Quanticel Research, Inc.] 154
- [GSK Pharmaceuticals R&D] 38
- [Neurodegeneration DPU, Neurosciences Therapeutic Area Unit, GSK Pharmaceuticals R&D, 898 Halei Road, Zhangjiang Hi-Tech Park, Pudong, Shanghai 201203, PR China.] 36
- [GlaxoSmithKline Medicine Research Centre] 32
- [Universit£ degli Studi di Siena] 27
- [GlaxoSmithKline Medicines Research Centre] 23
- [Rottapharm Madaus] 19
- [GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED] 18
- [ROTTAPHARM BIOTECH S.R.L., TBA] 16
- [ROTTAPHARM BIOTECH S.R.L., TBA] 16
Affinity: 0.078 to 1.0E+6 nM▿
- Ki 235
- IC50 306
- EC50 157
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 21