Compile Data Set for Download or QSAR
Found 278 from Mutabilis
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392744(7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-5-(hexahydro...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
GSK

LigandPNGBDBM392794(5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392769(1′-Cyclohexyl-6-[methyl-(2-pyrrolidin-1-yl-e...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
GSK

LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)copy SMILES
Affinity DataIC50: 3.60nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392795(7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...)copy SMILES
Affinity DataIC50: 4nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392795(7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...)copy SMILES
Affinity DataIC50: 4nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392774(US10301305, Example 136 | rac-1′-((trans)-3-...)copy SMILES
Affinity DataIC50: 4.30nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392785(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392801(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...)copy SMILES
Affinity DataIC50: 4.70nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392785(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392793(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...)copy SMILES
Affinity DataIC50: 5.10nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392779(1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392774(US10301305, Example 136 | rac-1′-((trans)-3-...)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecium E1679)
GSK

LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392793(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...)copy SMILES
Affinity DataIC50: 6.20nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392801(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...)copy SMILES
Affinity DataIC50: 6.5nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392781(1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...)copy SMILES
Affinity DataIC50: 6.70nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392786(6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392794(5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392767(6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILES
Affinity DataIC50: 6.90nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392789(7-(1-butylbenzimidazol-5-yl)-5-[2-(dimethylamino)e...)copy SMILEScopy InChI
Affinity DataIC50: 7.30nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50399411(CHEMBL2178304 | PT405)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99699PubMed
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392778(1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...)copy SMILEScopy InChI
Affinity DataIC50: 8.10nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392767(6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILES
Affinity DataIC50: 8.20nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392786(6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...)copy SMILEScopy InChI
Affinity DataIC50: 8.30nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392797(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[3-...)copy SMILES
Affinity DataIC50: 9nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392784(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[me...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392791(5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPeptidoglycan D,D-transpeptidase MrdA(Escherichia coli)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50512952(CHEMBL4560540)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of bocillin-FL binding to Escherichia coli K12 NusA-fused/His6-tagged PBP2 (57 to 615 residues) expressed in Escherichia coli BL21(DE3) pr...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ3BG7PubMed
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392742(US10301305, Example 6 | {1-[7-(1-Cyclohexyl-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392790(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392746(US10301305, Example 20 | {1-[4-(1-Cyclohexyl-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50399407(CHEMBL2178284 | MUT056399)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99699PubMed
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392777(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50399400(CHEMBL2178291)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392778(1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392779(1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392781(1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...)copy SMILES
Affinity DataIC50: 15nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392775(1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...)copy SMILES
Affinity DataIC50: 15nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392765(1′-Cyclohexyl-6-[(2-hydroxy-ethyl)-methyl-am...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus)
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50399404(CHEMBL2178287 | US8623865, 1)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H99699PubMed
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392777(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILEScopy InChI
Affinity DataIC50: 16nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392775(1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...)copy SMILES
Affinity DataIC50: 16nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392790(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetD-alanine--D-alanyl carrier protein ligase(Enterococcus faecalis (strain ATCC 700802 / V583))
GSK

LigandPNGBDBM392776(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392773(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
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