Found 61 of ic50 for monomerid = 138348 
Affinity DataIC50: 10nMAssay Description:Affinity evaluation of the tested compounds and their selectivity with respect to the different PARP isoforms of interest was assessed in a displacem...More data for this Ligand-Target Pair
3D Structure (crystal)TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of PARP1 in human HeLa cells assessed as reduction of H2O2-induced PAR formation preincubated for 30 mins followed by H2O2 addition measur...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 8.15E+3nMAssay Description:Inhibition of CYP2B6 in human liver microsomes after 20 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.51E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MNK2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EphA2More data for this Ligand-Target Pair
TargetProtein kinase C beta type(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKCbetaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
TargetDual specificity protein kinase TTK(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MPS1More data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human LYNMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human SYKMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human AKT1More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDK2/CYCAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human VEGFR2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human AUR2More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PKAalphaMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JAK3More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human IKK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PAK4More data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FLT3More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERK2More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase 26(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MST4More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EGFR1More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ALKMore data for this Ligand-Target Pair
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MAPKAPK2More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDGFRbMore data for this Ligand-Target Pair
TargetEukaryotic translation initiation factor 2-alpha kinase 3(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PERKMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase Nek6(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NEK6More data for this Ligand-Target Pair
TargetIGF-like family receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human IGFR1More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human KITMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIM2More data for this Ligand-Target Pair
TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CDC7/DBF4More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human RETMore data for this Ligand-Target Pair
TargetFibroblast growth factor receptor 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TRKAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ABLMore data for this Ligand-Target Pair
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human EEF2KMore data for this Ligand-Target Pair
TargetMaternal embryonic leucine zipper kinase(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human MELKMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human JAK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase NIM1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human NIM1More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PDK1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human PIM1More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase haspin(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human HaspinMore data for this Ligand-Target Pair
TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human BUB1More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FAKMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ACK1More data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human METMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase tousled-like 2(Homo sapiens (Human))
Nerviano Medical Sciences Srl
Curated by ChEMBL
Nerviano Medical Sciences Srl
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human TLK2More data for this Ligand-Target Pair
