Found 23 of ic50 for monomerid = 50366114 TargetAurora kinase B(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant aurora-B expressed in Sf9 cells using tetra(LRRWSLG) as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 8(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant COT expressed in Sf9 cells assessed as autophosphorylation after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetInsulin receptor(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant INS-R expressed in Sf9 cells using poly(A,E,K,Y)6:2:5:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant CDK2/CyclinA expressed in Sf9 cells using histone H1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
BMSSI UMR 5086 CNRS/Universit£ Lyon 1
Curated by ChEMBL
BMSSI UMR 5086 CNRS/Universit£ Lyon 1
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by FACS methodMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant AKT1 expressed in Sf9 cells using GSK3(14-27) as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetNUAK family SNF1-like kinase 1(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant ARK5 expressed in Sf9 cells assessed as autophosphorylation after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant aurora-A expressed in Sf9 cells using tetra(LRRWSLG) as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant B-RAF expressed in Sf9 cells using MEK1 KM as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant EGF-R expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant EPHB4 expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant ERBB2 expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetFocal adhesion kinase 1(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant FAK expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant IGF1R expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant SRC expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant VEGF-R2 expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant VEGF-R3 expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant MET expressed in Sf9 cells using poly(A,E,K,Y)6:2:5:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant PDGFRbeta expressed in Sf9 cells using poly(A,E,K,Y)6:2:5:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant PLK1 expressed in Sf9 cells using casein as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK4(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant SAK expressed in Sf9 cells using p38alpha-KRKR as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant TIE2 expressed in Sf9 cells using poly(E,Y)4:1 as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Westf£lische Wilhelms-Universit£t M£nster
Curated by ChEMBL
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human recombinant CDK4/CyclinD1 expressed in Sf9 cells using RB-CTF as substrate after 80 mins by scintillation countingMore data for this Ligand-Target Pair
