Compile Data Set for Download or QSAR
Found 7 of ki for UniProtKB: P51589
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Mixed inhibition of recombinant CYP2J2 (unknown origin)-mediated astemizole O-demethylation in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN97D2PubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method and Dixon plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataKi:  100nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS method and Dixon plotMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50017702(1-(bis(4-fluorophenyl)methyl)-4-cinnamylpiperazine...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Non-competitive inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50183079(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)-1-(4-p...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Inhibition of human recombinant CYP2J2 expressed in baculovirus-infected Sf9 insect cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z440RPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50043280(4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidaz...)copy SMILEScopy InChI
Affinity DataKi:  190nMAssay Description:Mixed type inhibition of human recombinant CYP2J2 assessed as reduction in astemizole O-demethylation by LC-MS/MS methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K0761GPubMed
TargetCytochrome P450 2J2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50088489(CHEMBL3527324)copy SMILEScopy InChI
Affinity DataKi:  2.40E+5nMAssay Description:Inhibition of recombinant CYP2J2 (unknown origin) treated with AMG 853More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z039WTPubMed