Compile Data Set for Download or QSAR
Found 39 of ki data for polymerid = 1179,1181,1191,50004780
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50541929(CHEMBL1738785)copy SMILEScopy InChI
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50554340(CHEMBL4788866)copy SMILES
Affinity DataKi:  17nMAssay Description:Inhibition of full-length C-terminal his-tagged human recombinant CHIT1 catalytic domain (1 to 386 residues) expressed in HEK293F cells assessed as r...More data for this Ligand-Target Pair
TargetEndochitinase B1(Aspergillus fumigatus)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM50173286(5-[3-[amino-(methylcarbamoylamino)methylidene]amin...)copy SMILEScopy InChI
Affinity DataKi:  17nMAssay Description:Inhihitory activity against Chitinase B1 (AfChiB1) using fuorometric assay with 4-methylumbelliferyl-b-D-N,N0-diacetylchitobiose as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MS3S9TPubMedMMDB
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM10854(4-[(1S,4R,10S,13S,16S,18R)-10-{3-[(acetamidomethan...)copy SMILEScopy InChI
Affinity DataKi:  20nM ΔG°:  -10.9kcal/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4MV6PubMed
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50514508(CHEMBL4549449)copy SMILEScopy InChI
Affinity DataKi:  49nMAssay Description:Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N019W8PubMed
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM50514507(CHEMBL1583158)copy SMILEScopy InChI
Affinity DataKi:  58nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N019W8PubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50022832(Rafoxanide)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61Q3PubMed
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM50587859(CHEMBL5180998)copy SMILES
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QN5PubMed
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM50587858(9-O-(Benzoyl)Berberrubine Chloride | CHEMBL1223325)copy SMILES
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QN5PubMed
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM50587857(CHEMBL5199149)copy SMILES
Affinity DataKi:  150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QN5PubMed
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50243745(CHEMBL4076989)copy SMILEScopy InChI
Affinity DataKi:  312nMAssay Description:Inhibition of human recombinant full length C-terminal His-tagged chitotriosidase expressed in CHO-K1 cells using 4-methylumbelliferyl-beta-D-N,N',N\...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J105J5PubMed
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50587857(CHEMBL5199149)copy SMILES
Affinity DataKi:  350nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28G8QN5PubMed
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM50514508(CHEMBL4549449)copy SMILEScopy InChI
Affinity DataKi:  410nMAssay Description:Inhibition of Serratia marcescens chitinase b catalytic domain overexpressed in Escherichia coli BL21(DE3) cells using 4MU-(GlcNAc)2 as substrate aft...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N019W8PubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50063753(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)copy SMILEScopy InChI
Affinity DataKi:  468nMAssay Description:Inhibition of Onchocerca volvulus L3 larvae chitinase using 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as a profluorescent substrate after 10 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FB9PubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50063753(CHEMBL12131 | Closantel | N-(5-chloro-4-((4-chloro...)copy SMILEScopy InChI
Affinity DataKi:  470nMAssay Description:Competitive inhibition of Onchocerca volvulus L3 larvae chitinase using 20 uM 4-methylumbelliferyl-N,N',N''-beta-chitotrioside as substrate after 10 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61Q3PubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50498224(CHEMBL3577757)copy SMILEScopy InChI
Affinity DataKi:  980nMAssay Description:Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53PTXPubMed
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50514507(CHEMBL1583158)copy SMILEScopy InChI
Affinity DataKi:  1.12E+3nMAssay Description:Inhibition of human CHIT1 catalytic domain overexpressed in Pichia pastoris using 4MU-(GlcNAc)2 as substrate after 30 mins by fluorescence based micr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N019W8PubMed
TargetChitinase(Onchocerca volvulus)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM100152(7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...)copy SMILEScopy InChI
Affinity DataKi:  3.78E+3nMAssay Description:Competitive inhibition of L3 larval stage of Onchocerca volvulus chitinase using 4-methylumbelliferyl-N-N'-N''-beta-chitotrioside as substrate assess...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53PTXPubMed
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614248(CHEMBL5265903)copy SMILES
Affinity DataKi:  4.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614249(CHEMBL5280316)copy SMILES
Affinity DataKi:  5.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614256(CHEMBL5272737)copy SMILES
Affinity DataKi:  5.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614250(CHEMBL5288210)copy SMILES
Affinity DataKi:  6.20E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614257(CHEMBL5287414)copy SMILES
Affinity DataKi:  6.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614247(CHEMBL5269695)copy SMILES
Affinity DataKi:  6.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614254(CHEMBL5289877)copy SMILES
Affinity DataKi:  6.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614246(CHEMBL5279325)copy SMILES
Affinity DataKi:  7.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50254171(CHEMBL4069120)copy SMILEScopy InChI
Affinity DataKi:  9.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614251(CHEMBL5268683)copy SMILES
Affinity DataKi:  1.24E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614259(CHEMBL5270383)copy SMILES
Affinity DataKi:  1.24E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614241(CHEMBL5280623)copy SMILES
Affinity DataKi:  1.40E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614258(CHEMBL5270387)copy SMILES
Affinity DataKi:  1.40E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614242(CHEMBL5272989)copy SMILES
Affinity DataKi:  1.59E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614240(CHEMBL5290508)copy SMILES
Affinity DataKi:  3.14E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitinase B(Serratia marcescens)
University of Dundee

LigandPNGBDBM10853((2R,5S,8S,11S,15S)-8-benzyl-2,7-dimethyl-5-[3-({[(...)copy SMILEScopy InChI
Affinity DataKi:  3.30E+4nM ΔG°:  -6.36kcal/molepH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23F4MV6PubMed
TargetEndochitinase B1(Aspergillus fumigatus)
University of Dundee

Curated by ChEMBL
LigandPNGBDBM10850(1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...)copy SMILEScopy InChI
Affinity DataKi:  3.70E+4nM ΔG°:  -6.28kcal/mole IC50: 1.26E+5nMpH: 5.5 T: 2°CAssay Description:The IC50s of inhibitor against the human chitinase were determined using the fluorogenic substrate 4MU-NAG3. The fluorescence of the liberated 4MU wa...More data for this Ligand-Target Pair
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614252(CHEMBL5283905)copy SMILES
Affinity DataKi: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614245(CHEMBL5283183)copy SMILES
Affinity DataKi: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614243(CHEMBL5279201)copy SMILES
Affinity DataKi: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetChitotriosidase-1(Homo sapiens (Human))TBA
LigandPNGBDBM50614255(CHEMBL5268303)copy SMILES
Affinity DataKi: >5.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails