Compile Data Set for Download or QSAR
Found 22 of ic50 data for polymerid = 2621
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.08E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.59E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.24E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)copy SMILEScopy InChI
Affinity DataIC50: 4.09E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.25E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 4.31E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.08E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24531((3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)copy SMILEScopy InChI
Affinity DataIC50: 7.25E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)copy SMILEScopy InChI
Affinity DataIC50: 7.34E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)copy SMILEScopy InChI
Affinity DataIC50: 7.42E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24538((3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+5nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed
TargetTyrosine-protein phosphatase non-receptor type 6 [205-595](Homo sapiens (Human))
Moffitt Cancer Center

LigandPNGBDBM24550(3-{2-[(3Z)-5-{[(3-chloro-4-fluorophenyl)methyl]sul...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+5nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD0ZZ8PubMed