Compile Data Set for Download or QSAR
Found 7 of ic50 data for polymerid = 2828
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25472(CHEMBL519123 | N-[4-(1H-pyrazol-4-yl)phenyl]-2,3-d...)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25474(JMC516642 Compound 5 | N-{2-[2-(dimethylamino)etho...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25473(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25470(N-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 7.20nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25471(N-[4-(pyridin-4-yl)phenyl]-2,3-dihydro-1,4-benzodi...)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25476(N-{2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 760nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed
TargetRho-associated protein kinase 2 [1-543,T431N](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM25475(2-[2-(dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)ani...)copy SMILEScopy InChI
Affinity DataIC50: 920nMpH: 7.0 T: 2°CAssay Description:Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9NRNPubMed