Compile Data Set for Download or QSAR
Found 53 of ic50 for UniProtKB: A0A509AEH5
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92606(DHOD Inhibitor, 5 | US8703811, 6)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92606(DHOD Inhibitor, 5 | US8703811, 6)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92604(DHOD Inhibitor, 3 | US8703811, 1)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92603(DHOD Inhibitor, 2 | US8703811, 3)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92603(DHOD Inhibitor, 2 | US8703811, 3)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92605(DHOD Inhibitor, 4 | US8703811, 5)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM92602(DHOD Inhibitor, 1 | US8703811, 2)copy SMILEScopy InChI
Affinity DataIC50: 560nMAssay Description:Assay was determined using a continuous assay.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5MFQPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28821(5-methyl-N-(4-nitrophenyl)-[1,2,4]triazolo[1,5-a]p...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28814(N-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM24412(5-methyl-N-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM120364(US8703811, 4)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WD3Z7PUS Patent
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28833(N-(3,4-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28841(4-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28816(5-methyl-N-(4-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28836(N-(4-fluoro-3-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28834(N-(3,5-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28820(N-[4-(difluoromethoxy)phenyl]-5-methyl-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28810(N-(3-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28818(N-(4-methoxyphenyl)-5-methyl-[1,2,4]triazolo[1,5-a...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28812(5-methyl-N-[3-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28813(N-(4-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28811(5-methyl-N-(3-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28809(N-(3-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28808(2-({5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl}...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28807(5-methyl-N-[2-(trifluoromethyl)phenyl]-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28806(5-methyl-N-(2-methylphenyl)-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28805(N-(2-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28804(N-(2-fluorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28827(5-methyl-N-(2,3,4-trifluorophenyl)-[1,2,4]triazolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28826(N-(2,6-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28823(N-(4-benzylphenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28824(N-(2,3-difluorophenyl)-5-methyl-[1,2,4]triazolo[1,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28835(N-[3,5-bis(trifluoromethyl)phenyl]-5-methyl-[1,2,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28832(N-(2-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28831(5-methyl-N-(2,3,4,5,6-pentafluorophenyl)-[1,2,4]tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei)
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College

US Patent
LigandPNGBDBM28830(5-methyl-N-(2,3,5,6-tetrafluorophenyl)-[1,2,4]tria...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN653CPubMed
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