Compile Data Set for Download or QSAR
Found 43 of ki for UniProtKB: P78527
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50156495(8-(dibenzo[b,d]thiophen-4-yl)-2-morpholino-4H-chro...)copy SMILEScopy InChI
Affinity DataKi:  0.650nMAssay Description:Inhibitory activity against DNA-dependent protein kinase receptorMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50341751(3-amino-6-(4-((1-(dimethylamino)propan-2-yl)sulfon...)copy SMILEScopy InChI
Affinity DataKi:  6nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F2GPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571473(CHEMBL4856420 | US11685734, Example 39)copy SMILES
Affinity DataKi:  7nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50594892(CHEMBL5192303)copy SMILES
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50594891(CHEMBL5171087)copy SMILES
Affinity DataKi: <100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8KKJPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571476(CHEMBL4852400 | US11685734, Example 215)copy SMILES
Affinity DataKi:  110nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Binding affinity for DNA dependent protein kinase isolated from HeLa cells; Range is 20-120More data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM15234((1R,3R,5S,9R,18S)-18-(methoxymethyl)-1,5-dimethyl-...)copy SMILEScopy InChI
Affinity DataKi:  120nMAssay Description:Inhibition of DNA-PK isolated from human HeLa cell extractMore data for this Ligand-Target Pair
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571459(CHEMBL4872830)copy SMILES
Affinity DataKi:  160nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50571464(CHEMBL4874640 | US11685734, Example 43)copy SMILES
Affinity DataKi:  180nMAssay Description:Inhibition of DNA-PK isolated from human HeLa nuclear extract using full length His-tagged p53 as substrate measured after 75 mins in presence of ATP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76HB1PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50274538(CHEMBL4126773)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Inhibition of DNA-PK (unknown origin) using EPPLSQEAFADLWKKK as substrate after 15 mins in presence of [33P-ATP] by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V98BK8PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513172(CHEMBL4467848)copy SMILEScopy InChI
Affinity DataKi:  785nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50093352(CHEMBL3586678)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of DNAPK (unknown origin) using ATP and PPLSQEAFADLWKKK substrate by radiometric peptide assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89F53PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513180(CHEMBL4593939)copy SMILEScopy InChI
Affinity DataKi: >1.60E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513173(CHEMBL4566104)copy SMILEScopy InChI
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513176(CHEMBL4448538)copy SMILEScopy InChI
Affinity DataKi:  2.61E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50341747(3-amino-6-(4-(isopropylsulfonyl)phenyl)-N-phenylpy...)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50549837(CHEMBL4759283)copy SMILES
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8081PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM420857(US10479784, Compound IIA-10 | US10961232, Compound...)copy SMILEScopy InChI
Affinity DataKi:  3.35E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50549828(CHEMBL4795990)copy SMILES
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8081PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50549855(CHEMBL4756664)copy SMILES
Affinity DataKi:  3.50E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8081PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513181(CHEMBL4440048)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM132734(US8846917, I-1)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513182(CHEMBL4473876)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM420860(US10479784, Compound IIA-13 | US10961232, Compound...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50437436(CHEMBL2409216 | US8841450, I-1)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513175(CHEMBL4530813)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513174(CHEMBL4445532)copy SMILEScopy InChI
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513178(CHEMBL4434665)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM420852(US10479784, Compound IIA-5 | US10961232, Compound ...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM350085(3-[3-[4-[dideuterio(methylamino)methyl]phenyl]isox...)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513177(CHEMBL4444602)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50513179(CHEMBL4558884)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50093351(CHEMBL3585362)copy SMILEScopy InChI
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of DNAPK (unknown origin) using ATP and PPLSQEAFADLWKKK substrate by radiometric peptide assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89F53PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Affinity for DNA-dependent protein kinase(DNA-PK) from HeLa cell extractMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2WS8SP4PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of DNA-PK (unknown origin) in the presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RF5WFDPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)copy SMILEScopy InChI
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of DNA-PKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23J3F2GPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50549854(CHEMBL4784202)copy SMILES
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8081PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50549846(CHEMBL4764646)copy SMILES
Affinity DataKi: >7.00E+3nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HD8081PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM420609(US10479784, Compound IA-116 | US10961232, Compound...)copy SMILEScopy InChI
Affinity DataKi:  8.90E+3nMAssay Description:Inhibition of purified recombinant human full-length DNA-PK using EPPLSQEAFADLWKKK peptide as substrate measured after 2 hrs in presence of [gamma-33...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ69C9PubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50463483(CHEMBL4245242)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DNAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85HXPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DNAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85HXPubMed
TargetDNA-dependent protein kinase catalytic subunit(Homo sapiens (Human))
School of Natural Sciences--Chemistry

Curated by ChEMBL
LigandPNGBDBM50463484(CHEMBL4248525)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of DNAPK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85HXPubMed