Compile Data Set for Download or QSAR
Found 30 of ic50 data for polymerid = 49000775,49000776,9680
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50416397(CHEMBL1210515)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JSGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959JSGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50381980(CHEMBL2022495)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at alpha1 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FZCPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50413330(CHEMBL459689)copy SMILEScopy InChI
Affinity DataIC50: 3.98E+3nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM875BPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352784(CHEMBL1823380)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352785(CHEMBL1823381)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50472282(descyanothiacloprid)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50382048(CHEMBL2022739)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at alpha1 nAChRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB46SHPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)copy SMILEScopy InChI
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM875BPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352786(CHEMBL1823382)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50078044(3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-(2E)-yl...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352788(CHEMBL1823384)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352791(CHEMBL1823387)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352790(CHEMBL1823386)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352789(CHEMBL1823385)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50352787(CHEMBL1823383)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VWPPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50078048(1-(6-Chloro-pyridin-3-ylmethyl)-imidazolidin-(2Z)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50310000(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of nAChR alpha1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89FZDPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50550026(CHEMBL4786690)copy SMILES
Affinity DataIC50: 1.23E+4nMAssay Description:Inhibition of alpha1 nAChR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7FR5PubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50247983(CHEMBL454407 | cis-1-methyl-5-(phenylethynyl)-3-(p...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM875BPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50443541(CHEMBL3091687)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of nAChR alpha1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89FZDPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75F64PubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50310000(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of nAChR alpha1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89FZDPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50487992(CHEMBL2270633)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50413331(CHEMBL459900)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM875BPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50251868((Z)-thiacloprid | CHEMBL451432 | {(2Z)-3-[(6-chlor...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50248045((S)-1-(2-fluorophenyl)ethyl (S)-quinuclidin-3-ylca...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+5nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GM875BPubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University of California

Curated by ChEMBL
LigandPNGBDBM50212288((2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimida...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1NGGPubMed