Compile Data Set for Download or QSAR
Found 8 of ic50 data for polymerid = 50000603
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50263327(CHEMBL476339 | N-(4-methylpyridin-2-yl)-4-(pyridin...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:Inhibition of Kca2.2 channel expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275960(5-chloro-N-(thiophen-2-ylmethyl)pyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 530nMAssay Description:Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 543nMAssay Description:Displacement of [125I]apamin from Kca2.2 channel expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N87BP1PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50275792(CHEMBL452406 | N-benzyl-5-chloropyrazolo[1,5-a]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Kca2.2 channel (unknown origin) expressed in HEK293 cells by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM79Z6PubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50377863(AG-525 | CHEMBL257156)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of SK2 expressed in CHO FlipIn cells by whole cell patch-clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N29XTJPubMed
TargetSmall conductance calcium-activated potassium channel protein 2(Homo sapiens (Human))
Bristol Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50507839(PF-6305591 | Pf-06305591)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5KZNPubMed