Compile Data Set for Download or QSAR
Found 168 of ic50 data for polymerid = 50001107
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283602(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908TCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18355((2R,3R,4R,5S)-1-butyl-2-(hydroxymethyl)piperidine-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736QZBPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM628474(US20230339856, Compound (IId))copy SMILES
Affinity DataIC50: 150nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM628473(US20230339856, Compound (IIc))copy SMILES
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50478556(CORTICATIC ACID A)copy SMILEScopy InChI
Affinity DataIC50: 344nMAssay Description:Inhibition of alpha-glucosidaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004T1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 350nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50583379(CHEMBL5028138 | US20230339856, Compound (IIb))copy SMILES
Affinity DataIC50: 390nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908TCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736QZBPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50583378(CHEMBL5028084 | US20230339856, Compound (IIa))copy SMILES
Affinity DataIC50: 420nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50124581(CHEMBL3621529 | US20230339856, Compound (IIg))copy SMILEScopy InChI
Affinity DataIC50: 460nMMore data for this Ligand-Target Pair
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50312529(CHEMBL1088158 | N-[5-(Adamantan-1-yl-methoxy)-pent...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908TCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50478555(Callyspongynic Acid)copy SMILEScopy InChI
Affinity DataIC50: 531nMAssay Description:Inhibition of alpha-glucosidaseMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20004T1PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50596693(CHEMBL5189075)copy SMILES
Affinity DataIC50: 630nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VSCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)copy SMILEScopy InChI
Affinity DataIC50: 750nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM628475(US20230339856, Compound (IIf))copy SMILES
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398032(CHEMBL1603014)copy SMILEScopy InChI
Affinity DataIC50: 940nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283602(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 999nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283602(6a-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 999nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50259956(2,6-Bis-hydroxymethyl-piperidine-3,4,5-triol | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283598(5-Amino-1-hydroxymethyl-cyclopentane-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibitory activity against baker's yeast Alpha-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398022(CHEMBL2181097)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human lysosomal alpha glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736QZBPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908TCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50312528(CHEMBL1086997 | N-Butyl-D-galacto-1-deoxynojirimyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M908TCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398020(CHEMBL2181103)copy SMILEScopy InChI
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50242271((2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of lysosomal alpha-glucosidase by HPLCMore data for this Ligand-Target Pair
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50104671(CHEMBL3593568)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of alpha-glucosidase (unknown origin) pre-incubated for 20 mins before p-nitrophenyl glycoside substrate additionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C82C20PubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283603(4-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398029(CHEMBL2180814)copy SMILEScopy InChI
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50596691(CHEMBL5198563)copy SMILES
Affinity DataIC50: 2.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VSCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)copy SMILEScopy InChI
Affinity DataIC50: 2.91E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283604(6-Hydroxymethyl-2-phenylamino-4,5,6,6a-tetrahydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibitory activity was determined against baker's yeast Alpha-GlucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5FFN
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398028(CHEMBL2180816)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)copy SMILEScopy InChI
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398024(CHEMBL2181095)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398027(CHEMBL2181089)copy SMILEScopy InChI
Affinity DataIC50: 3.66E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using blue-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50596692(CHEMBL5192700)copy SMILES
Affinity DataIC50: 3.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24F1VSCPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50398024(CHEMBL2181095)copy SMILEScopy InChI
Affinity DataIC50: 4.11E+3nMAssay Description:Inhibition of wild type recombinant GAA preincubated for 5 mins measured after 45 mins using red-shifted dye by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27945SSPubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2W2BPubMed
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