Compile Data Set for Download or QSAR
Found 124 of ic50 data for polymerid = 50001213
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353115(CHEMBL1829127)copy SMILEScopy InChI
Affinity DataIC50: 0.0680nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353110(CHEMBL1829122)copy SMILEScopy InChI
Affinity DataIC50: 0.0730nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353113(CHEMBL1829125)copy SMILEScopy InChI
Affinity DataIC50: 0.0840nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353114(CHEMBL1829126)copy SMILEScopy InChI
Affinity DataIC50: 0.0910nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353111(CHEMBL1829123)copy SMILEScopy InChI
Affinity DataIC50: 0.110nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353097(CHEMBL1829132)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353116(CHEMBL1829128)copy SMILEScopy InChI
Affinity DataIC50: 0.530nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353098(CHEMBL1829133)copy SMILEScopy InChI
Affinity DataIC50: 0.560nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353103(CHEMBL1829139)copy SMILEScopy InChI
Affinity DataIC50: 0.670nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353102(CHEMBL1829138)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50378116(CHEMBL1202327)copy SMILEScopy InChI
Affinity DataIC50: 0.940nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353105(CHEMBL1829117)copy SMILEScopy InChI
Affinity DataIC50: 1.06nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353099(CHEMBL1829134)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297583(CHEMBL560806 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)copy SMILEScopy InChI
Affinity DataIC50: 1.17nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207580(CHEMBL234074 | N-[3-(5-nitro-1H-benzoimidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.42nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50353101(CHEMBL1829137)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297577(CHEMBL549392 | N''-[2-(1H-benzimidazol-2-ylthio)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.73nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297571(CHEMBL561343 | N''-{2-[(5-nitro-1H-benzimidazol-2-...)copy SMILEScopy InChI
Affinity DataIC50: 1.74nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)copy SMILEScopy InChI
Affinity DataIC50: 1.82nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat assessed as inhibition of acid-induced platelet swelling by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27081T0PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297563(CHEMBL550813 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297578(2-{[(1E)-2-(1,3-benzothiazol-2-ylsulfanyl)-4,5,6-t...)copy SMILEScopy InChI
Affinity DataIC50: 1.98nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297580(CHEMBL560884 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.34nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297562(CHEMBL563178 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.44nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345911(CHEMBL1783852 | CHEMBL1789669 | N-(diaminomethylen...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207583(CHEMBL234279 | N-[2-(5-nitro-1H-benzoimidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 4.05nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345917(CHEMBL1783857 | N-(diaminomethylene)-3-(N-methylsu...)copy SMILEScopy InChI
Affinity DataIC50: 4.48nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297575(2-{[(1E)-2-(1H-1,3-benzodiazol-2-ylsulfanyl)-4,5,6...)copy SMILEScopy InChI
Affinity DataIC50: 10.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207572(CHEMBL234072 | N-[4-(5-nitro-1H-benzoimidazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345908(CHEMBL1783849 | N-(diaminomethylene)-2-((4-(2,3,4-...)copy SMILEScopy InChI
Affinity DataIC50: 11.1nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297576(CHEMBL561142 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)copy SMILEScopy InChI
Affinity DataIC50: 11.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345914(CHEMBL1783830 | N-(diaminomethylene)-3-sulfamoyl-4...)copy SMILEScopy InChI
Affinity DataIC50: 11.5nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297569(CHEMBL563763 | N''-{5-chloro-2-[(5-nitro-1H-benzim...)copy SMILEScopy InChI
Affinity DataIC50: 12.2nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115243((S)-N-[7-(5-fluoro-2-methylphenyl)-4-methyl-(7S)-5...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345912(CHEMBL1783853 | N-(diaminomethylene)-4-nitro-3-((4...)copy SMILEScopy InChI
Affinity DataIC50: 14.2nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345916(CHEMBL1783856 | N-(diaminomethylene)-3-(N-methylsu...)copy SMILEScopy InChI
Affinity DataIC50: 15nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297566(CHEMBL549925 | N''-{2-[(5-methoxy-1H-benzimidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 16.8nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115239((S)-N-[7-(2,5-dichloro-3-thienyl)-4-methyl-(7S)-5,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50345913(CHEMBL1783854 | N-(diaminomethylene)-3-nitro-4-(1-...)copy SMILEScopy InChI
Affinity DataIC50: 18.7nMAssay Description:Inhibition of NHE1-mediated rat platelet swellingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BR8SJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115246(CHEMBL543867 | N-[7-(2-chloro-5-fluorophenyl)-4-me...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115248(CHEMBL552723 | N-[7-(3-chloro-2-thienyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115271(CHEMBL556009 | N-[7-(2,5-dichloro-3-thienyl)-4-met...)copy SMILEScopy InChI
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115267(CHEMBL102546 | N-[7-(2-chlorophenyl)-4-methyl-(7S)...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297579(CHEMBL550335 | N''-[2-(1,3-benzothiazol-2-ylthio)-...)copy SMILEScopy InChI
Affinity DataIC50: 20.3nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297574(CHEMBL557259 | N''-[2-(1H-benzimidazol-2-ylthio)-5...)copy SMILEScopy InChI
Affinity DataIC50: 21.4nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115268(CHEMBL554001 | N-[7-(2-chloro-3-thienyl)-4-methyl-...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50297564(CHEMBL550611 | N''-{6-fluoro-2-[(5-methoxy-1H-benz...)copy SMILEScopy InChI
Affinity DataIC50: 25.5nMAssay Description:Inhibition of NHE1 in Sprague-Dawley rat platelet-rich plasma by optical swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BS7PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115238(CHEMBL552865 | N-[7-(2-chlorophenyl)-4-methyl-5,6,...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207574(CHEMBL233048 | N-{3-(morpholine-4-sulfonyl)-4-[4-(...)copy SMILEScopy InChI
Affinity DataIC50: 27.1nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50207579(CHEMBL232838 | N-{3-methanesulfonyl-4-[4-(5-nitro-...)copy SMILEScopy InChI
Affinity DataIC50: 27.8nMAssay Description:Inhibition of NHE1 in rat platelets by Platelet swelling assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21C1WJ1PubMed
TargetSodium/hydrogen exchanger 1(Rattus norvegicus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50115245(CHEMBL554215 | N-[4-methyl-7-(3-thienyl)-5,6,7,8-t...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:In vitro inhibition of acid induced swelling in rat platelets by 50% as a measure of NHE-1 inhibitionMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V40VZNPubMed
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