Compile Data Set for Download or QSAR
Found 18 of ic50 data for polymerid = 50003672
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191327(CHEMBL3960997)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50250399(5-Hydroxy-4-{(R)-6-hydroxy-5-[(E)-4-methyl-6-(2,6,...)copy SMILEScopy InChI
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues)-mediated TLS past acrolein derived ring-opened reduced form of gamma-HOPdG lesions prei...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50356642(CHEMBL1917196)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0989PubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50356643(CHEMBL1917198)copy SMILEScopy InChI
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (amino acids 1 to 560) using poly(dA)/oligo(dT)18 (A/T = 2/1) and dTTP as the DNA tem...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ0989PubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50318907(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)copy SMILEScopy InChI
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50104668(CHEMBL3593571)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of C-terminal His6-tagged human DNA polymerase kappa (1 to 560 residues) expressed in Escherichia coli using poly(dA)/oligo(dT)18 and [3H]...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50191327(CHEMBL3960997)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human DNA polymerase kappa (19 to 526 residues) preincubated for 15 mins followed by replicating non-damaged DNA substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC84TJPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50379292(CHEMBL2011646)copy SMILEScopy InChI
Affinity DataIC50: 4.86E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154NGPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50379293(CHEMBL2011648)copy SMILEScopy InChI
Affinity DataIC50: 5.98E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154NGPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50375301(CHEMBL260980)copy SMILEScopy InChI
Affinity DataIC50: 5.98E+4nMAssay Description:Inhibition of human DNA polymerase kappaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HSTPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50375300(TALAROFLAVONE)copy SMILEScopy InChI
Affinity DataIC50: 8.65E+4nMAssay Description:Inhibition of human DNA polymerase kappaMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67HSTPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50379294(CHEMBL2011647)copy SMILEScopy InChI
Affinity DataIC50: 8.89E+4nMAssay Description:Inhibition of human C-terminal-His6-tagged DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into po...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154NGPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50448689(CHEMBL3127730)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2HMWPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50448690(CHEMBL3127728)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2HMWPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50448691(CHEMBL3127729)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2HMWPubMed
TargetDNA polymerase kappa(Homo sapiens (Human))
University of Connecticut Health Center

Curated by ChEMBL
LigandPNGBDBM50448688(Pecilocin | Variotin)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of C-terminal His-6-tagged human DNA polymerase kappa expressed in Escherichia coli assessed as inhibition of incorporation of dTTP into p...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22V2HMWPubMed