Compile Data Set for Download or QSAR
Found 10 of ic50 data for polymerid = 6314
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531902(CHEMBL4569405)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM124261(2-((5-Bromo-2-oxybenzylidene)amino)benzoato-diaqua...)copy SMILEScopy InChI
Affinity DataIC50: 600nMpH: 7.2Assay Description:The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ070WPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM124260(2-((5-Bromo-2-oxybenzylidene)amino)benzoato-diaqua...)copy SMILEScopy InChI
Affinity DataIC50: 970nMpH: 7.2Assay Description:The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ070WPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM124263(Bis(4-bromo-2-((phenylimino)methyl)phenolate)-oxov...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMpH: 7.2Assay Description:The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ070WPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM124264(Bis(4-nitro-2-((phenylimino)methyl)phenolate)-oxov...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 7.2Assay Description:The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ070WPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM124262(Bis(4-chloro-2-((phenylimino)methyl)phenolate)-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMpH: 7.2Assay Description:The assays were performed in 20 mM MOPS buffer, pH 7.2, containing 50 mM NaCl and 2 mM GSH. Compounds were dissolved in DMSO and diluted to various c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ070WPubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531901(CHEMBL4540813)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM231167(US9340574, 7)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.0Assay Description:PTP activity was assayed using p-nitrophenyl phosphate (pNPP) as a substrate in 3,3-dimethylglutarate buffer (50 mM 3,3-dimethylglutarate, pH 7.0, 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NV9H4JUS Patent
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50531903(CHEMBL4530344)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged MEG1 catalytic domain (637 to 926 residues) expressed in Escherichia coli using p-nitrophenol a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NC64P6PubMed
TargetTyrosine-protein phosphatase non-receptor type 4(Homo sapiens (Human))
V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine

Curated by ChEMBL
LigandPNGBDBM50107739(CHEMBL140954 | [(4-{4-[4-(Difluoro-phosphono-methy...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase PTPmeg-1.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21Z455DPubMed