TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 24nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2B NMDA expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 111nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 170nMAssay Description:Compound was evaluated for in vitro inhibition of [3H]L-689,560 at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 220nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 231nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 263nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Compound was evaluated for in vitro inhibition of cortical slice release at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 560nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Binding affinity against phencyclidine receptor was determined by the displacement of [3H]-TCP of whole rat brain minus cerebellum.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Concentration required for 50% Inhibition of responses at cloned NR1A/2AB N-methyl-D-aspartate (NMDA) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 710nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 770nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 780nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 790nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 910nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 950nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of rat NMDA NR2C receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellul...More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Compound was evaluated for in vitro inhibition of oocytes at NMDA receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Compound was evaluated for in vitro inhibition of spinal cord at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Concentration required to inhibit of N-methyl-D-aspartic acid (NMDA) receptor produced by oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.30E+3nMAssay Description:Concentration required to inhibit of N-methyl-D-aspartic acid (NMDA) receptor produced by oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of [3H]1-[1-(2-thienyl) piperidine ([3H]TCP) binding to PCP receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Compound was evaluated for in vitro inhibition of cGMP cerebellar slice at NMDA receptor.More data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.20E+3nMAssay Description:Compound was evaluated for in vitro inhibition of oocytes at NMDA receptorMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2C(Rattus norvegicus (Rat))
CoCensys, Inc.
Curated by ChEMBL
CoCensys, Inc.
Curated by ChEMBL
Affinity DataIC50: 3.60E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2C receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair