Compile Data Set for Download or QSAR
Found 7 of ic50 data for polymerid = 9480
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223981(6,7-Dichloro-N-cyclopentyl-4-(pyridin-4-yl)phthala...)copy SMILEScopy InChI
Affinity DataIC50: 144nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223980(6,7-Dichloro-N-cyclopentylquinolin-4-amine (2))copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223979(7-Chloro-N-cyclopentylquinolin-4-amine (1))copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM223982((6,7-Dichloro-4-(cyclopentylamino)phthalazin-1-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:Experiments were performed in triplicate at room temperature with 1 h incubation of 10 μl reaction mixture in buffer of 20 mM Tris-HCl, pH 8.0, ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X065XFPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM50063670(CHEMBL3397332)copy SMILES
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CSSPubMed
TargetHistone-lysine N-methyltransferase KMT5C(Homo sapiens (Human))
AbbVie

LigandPNGBDBM50051117(CHEMBL3318285)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of SUV420H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J9681QPubMed