Compile Data Set for Download or QSAR
Found 49 of ec50 data for complexid = 50000039,50000062
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108998(CHEMBL3600560)copy SMILEScopy InChI
Affinity DataEC50:  8.60nMAssay Description:Agonist activity at human recombinant GABA-B receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155F6PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593659(CHEMBL5207265)copy SMILES
Affinity DataEC50:  64nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593660(CHEMBL5170235)copy SMILES
Affinity DataEC50:  90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593653(CHEMBL5185974)copy SMILES
Affinity DataEC50:  97nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593654(CHEMBL5204436)copy SMILES
Affinity DataEC50:  142nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593650(CHEMBL5169533)copy SMILES
Affinity DataEC50:  199nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24185((3-aminopropyl)(methyl)phosphinic acid | 3-Apmpa |...)copy SMILEScopy InChI
Affinity DataEC50:  200nMAssay Description:Inhibition of mammalian Gamma-aminobutyric acid type B receptor (potent agonist)More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593656(CHEMBL5183971)copy SMILES
Affinity DataEC50:  208nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593657(CHEMBL5187574)copy SMILES
Affinity DataEC50:  294nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593658(CHEMBL5193733)copy SMILES
Affinity DataEC50:  341nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593652(CHEMBL5188066)copy SMILES
Affinity DataEC50:  419nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593649(CHEMBL5202253)copy SMILES
Affinity DataEC50:  444nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593651(CHEMBL5186902)copy SMILES
Affinity DataEC50:  496nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataEC50:  530nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593655(CHEMBL5209256)copy SMILES
Affinity DataEC50:  637nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM86283(CAS_345-78-8 | CAS_39069-52-8 | GS 39783 | N,N'...)copy SMILEScopy InChI
Affinity DataEC50:  741nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593661(CHEMBL2346820)copy SMILES
Affinity DataEC50:  764nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50593648(CHEMBL5209395)copy SMILES
Affinity DataEC50:  771nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G164SJPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477169(CHEMBL393066)copy SMILEScopy InChI
Affinity DataEC50:  871nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50032964((R)-4-Amino-3-(4-chloro-phenyl)-butyric acid | 4-A...)copy SMILEScopy InChI
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477174(CHEMBL391647)copy SMILEScopy InChI
Affinity DataEC50:  1.20E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477175(CHEMBL276131)copy SMILEScopy InChI
Affinity DataEC50:  1.66E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477168(CHEMBL393269)copy SMILEScopy InChI
Affinity DataEC50:  1.66E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477177(CHEMBL237801)copy SMILEScopy InChI
Affinity DataEC50:  1.66E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)copy SMILEScopy InChI
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427614(CHEMBL2322946)copy SMILEScopy InChI
Affinity DataEC50:  1.90E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477173(CHEMBL392365)copy SMILEScopy InChI
Affinity DataEC50:  2.04E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477172(CHEMBL237582)copy SMILEScopy InChI
Affinity DataEC50:  2.75E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477171(CHEMBL401437)copy SMILEScopy InChI
Affinity DataEC50:  3.47E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477176(CHEMBL237581)copy SMILEScopy InChI
Affinity DataEC50:  4.57E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50477170(CHEMBL391576)copy SMILEScopy InChI
Affinity DataEC50:  5.01E+3nMAssay Description:Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2N300RDPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50108996(CGP-7930 | CHEMBL1256697)copy SMILEScopy InChI
Affinity DataEC50:  5.37E+3nMAssay Description:Positive allosteric modulator activity at GABA-B receptor (unknown origin) assessed as potentiation of 1 uM GABA-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T155F6PubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)copy SMILEScopy InChI
Affinity DataEC50:  1.59E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)copy SMILEScopy InChI
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427603(CHEMBL2322934)copy SMILEScopy InChI
Affinity DataEC50:  3.78E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427613(CHEMBL2322935)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427612(CHEMBL2322942)copy SMILEScopy InChI
Affinity DataEC50:  5.35E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427611(CHEMBL2322939)copy SMILEScopy InChI
Affinity DataEC50:  6.18E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427610(CHEMBL2322940)copy SMILEScopy InChI
Affinity DataEC50:  6.69E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427609(CHEMBL2322941)copy SMILEScopy InChI
Affinity DataEC50:  9.93E+4nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427604(CHEMBL2322936)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427605(CHEMBL2322932)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427607(CHEMBL2322944)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427608(CHEMBL2322943)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427606(CHEMBL2322945)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427601(CHEMBL2322938)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50427602(CHEMBL2322937)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MTSPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Homo sapiens (Human))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+5nMAssay Description:Antagonist activity at human recombinant GABAb 1b/2 receptor expressed in Xenopus laevis oocytes co-expressing GIRK1/4 assessed as inhibition of GABA...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FX79QRPubMed
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50211642(CHEMBL397209 | Methyl(1,2,3,6-tetrahydropyridinium...)copy SMILEScopy InChI
Affinity DataEC50:  5.00E+5nMAssay Description:Inhibition of rat hippocampal Gamma-aminobutyric acid type B receptor (weak agonist)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DV1KC9