Affinity DataKi: 1.98E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(Homo sapiens (Human))
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataKi: 3.57E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataKi: 3.69E+3nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataKi: 6.30E+3nMAssay Description:Binding affinity to rat GluA2-LBD (GluR2-S1S2J)More data for this Ligand-Target Pair
Affinity DataKi: 7.45E+3nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 1 in HEK293 cells using [3H]-AMPA as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 7.45E+3nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 1 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 7.50E+3nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 1 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(Homo sapiens (Human))
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
Affinity DataKi: 1.22E+4nMAssay Description:Binding affinity of compound was determined against Ionotropic glutamate receptor AMPA 2 using cell membranes prepared from HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+4nMAssay Description:Displacement of [3H]AMPA from human Ionotropic glutamate receptor AMPA 2 expressed in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.22E+4nMAssay Description:Compound was tested for binding affinity against human Ionotropic glutamate receptor AMPA 2 in HK293 cells using [3H]-AMPA as radioligandMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Agonist activity at rat recombinant GluR3 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataEC50: 3.80E+5nMAssay Description:Agonist activity at rat recombinant GluR2(Q) RNA-edited isoform expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+4nMAssay Description:Agonist activity at recombinant GluA1 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 7.30E+4nMAssay Description:Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataEC50: 4.70E+4nMAssay Description:Agonist activity at rat recombinant GluR4 flip isomer expressed in HEK293 cells assessed as increase in intracellular calcium level by Fluo-4/AM assa...Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Agonist activity at rat recombinant GluA3 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataEC50: 3.80E+5nMAssay Description:Agonist activity at rat recombinant GluA2 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+4nMAssay Description:Agonist activity at rat recombinant GluA3 receptor flop isoform expressed in Xenopus oocytesMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(Homo sapiens (Human))
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
SIBIA Neurosciences, Inc.
Curated by PDSP Ki Database
Affinity DataEC50: 2.66E+4nMAssay Description:Agonist activity at recombinant GluA3 receptor flop isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
Affinity DataEC50: 1.06E+4nMAssay Description:Agonist activity at recombinant GluA2 receptor flop isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
Affinity DataEC50: 7.51E+3nMAssay Description:Agonist activity at recombinant GluA1 receptor flip isoform expressed in Xenopus oocytes co-expressing gamma2-TARPMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
European Research Centre for Drug Discovery and Development (NatSynDrugs)
Curated by ChEMBL
Affinity DataEC50: 4.70E+4nMAssay Description:Agonist activity at rat recombinant GluA4 receptor flip isoform expressed in HEK293 cells assessed as effect on cyclothiazide-induced calcium flux by...More data for this Ligand-Target Pair