Compile Data Set for Download or QSAR
Found 3 of affinity data with PDB=4ASK
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Inhibition of KDM6B (unknown origin)More data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
TargetLysine-specific demethylase 6B(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM60875(3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...)copy SMILEScopy InChI
Affinity DataIC50: 160nMpH: 7.5Assay Description:The demethylase AlphaScreen assay was performed in 384-well plate format using white proxiplates (PerkinElmer), and transfer of compound (100 nl) was...More data for this Ligand-Target Pair