Affinity DataEC50: 10nMAssay Description:Inhibition of BCL-XL (unknown origin) expressed in mcl-1 deficient MEF assessed as induction of cell killing incubated for 48 hrs in presence of 10% ...More data for this Ligand-Target Pair
Affinity DataEC50: 18.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 18nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inhibition of BCL-XL (unknown origin) expressed in mcl-1 deficient MEF assessed as induction of cell killing incubated for 48 hrs in presence of 10% ...More data for this Ligand-Target Pair
Affinity DataEC50: 22.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: 1nM IC50: 100nM EC50: 22nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 30.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataEC50: 30.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 30nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 35.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 60nM EC50: 35nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 38nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 40nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 48nMAssay Description:Inhibition of BCL-XL (unknown origin) expressed in mcl-1 deficient MEF assessed as induction of cell killing in presence of 10% FBSMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 56.0nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 56nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 56nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 58nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 60nMAssay Description:Inhibition of BCL-XL (unknown origin) expressed in mcl-1 deficient MEF assessed as induction of cell killing incubated for 48 hrs in presence of 10% ...More data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 77nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 95nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 95.1nMAssay Description:Inhibition of Bcl-XLMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 60nM EC50: 100nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 118nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 125nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataEC50: 127nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 60nM EC50: 130nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 71nM EC50: 150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: <0.5nM ΔG°: <-53.1kJ/mole IC50: 300nM EC50: 150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: 1.10nM ΔG°: -51.1kJ/mole IC50: 75nM EC50: 150nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 159nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 83nM EC50: 160nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: <0.5nM IC50: 140nM EC50: 180nMAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataKi: 0.900nM ΔG°: -51.6kJ/mole IC50: 79nM EC50: 180nMpH: 7.4 T: 2°CAssay Description:The binding affinities (Ki) of compounds were determined using fluorescence polarization assays (FPA) that measure their ability to competitively dis...More data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Binding affinity to recombinant Bcl-XL (unknown origin) expressed in Escherichia coli BL21 by fluorescence polarization assayMore data for this Ligand-Target Pair