Compile Data Set for Download or QSAR
Found 90 of ec50 data for polymerid = 4981
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50394779(CHEMBL2163394)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0971FPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50394785(CHEMBL2163404)copy SMILEScopy InChI
Affinity DataEC50:  3nMAssay Description:Inhibition of Aurora kinase B in human HCT116 cells assessed as induction of 8N polyploidyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0971FPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50453822(CHEMBL3969370)copy SMILEScopy InChI
Affinity DataEC50:  7.10nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06CBPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50453821(CHEMBL4206831)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06CBPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326206(CHEMBL1243200 | N-(4-(3-(2-(Methylamino)pyrimidin-...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326207(CHEMBL1243294 | N-(4-(3-(2-(Methylamino)pyrimidin-...)copy SMILEScopy InChI
Affinity DataEC50:  15nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460772(CHEMBL4225923)copy SMILEScopy InChI
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460785(CHEMBL4226438)copy SMILEScopy InChI
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460772(CHEMBL4225923)copy SMILEScopy InChI
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460784(CHEMBL4227029)copy SMILEScopy InChI
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460791(CHEMBL4227284)copy SMILEScopy InChI
Affinity DataEC50: <16nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326211(5-Fluoro-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)py...)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326208(4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimid...)copy SMILEScopy InChI
Affinity DataEC50:  24nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460767(CHEMBL4228240)copy SMILEScopy InChI
Affinity DataEC50:  24nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50059435(CHEMBL3393498)copy SMILES
Affinity DataEC50:  27nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in histone H3 phosphorylation at S10 residues after 4 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ06CBPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326210(2-(4-Fluorophenylamino)-N-(4-(3-(2-(methylamino)py...)copy SMILEScopy InChI
Affinity DataEC50:  28nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50335179(6-Methyl-N-[3-(1-piperidinylmethyl)-5-isothiazolyl...)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460772(CHEMBL4225923)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50381996(CHEMBL2022373)copy SMILEScopy InChI
Affinity DataEC50:  58nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50381998(CHEMBL2022711)copy SMILEScopy InChI
Affinity DataEC50:  62nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50381997(CHEMBL2022379)copy SMILEScopy InChI
Affinity DataEC50:  83nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460778(CHEMBL4226184)copy SMILEScopy InChI
Affinity DataEC50:  83nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460789(CHEMBL4228308)copy SMILEScopy InChI
Affinity DataEC50:  88nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50326204(CHEMBL1243137 | N-(3-Methyl-4-(3-(2-(methylamino)p...)copy SMILEScopy InChI
Affinity DataEC50:  89nMAssay Description:Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst stainingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C829H0PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460770(CHEMBL4225181)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50073587(CHEMBL3408947 | US10358436, Example A185 | US20230...)copy SMILES
Affinity DataEC50:  102nMAssay Description:Inhibition of AURKB (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4SBVPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50073587(CHEMBL3408947 | US10358436, Example A185 | US20230...)copy SMILES
Affinity DataEC50:  102nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CZ3C5MPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382021(CHEMBL2022713)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460773(CHEMBL4227082)copy SMILEScopy InChI
Affinity DataEC50:  117nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382001(CHEMBL2022120)copy SMILEScopy InChI
Affinity DataEC50:  129nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382020(CHEMBL2022712)copy SMILEScopy InChI
Affinity DataEC50:  164nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460776(CHEMBL4227538)copy SMILEScopy InChI
Affinity DataEC50:  170nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460787(CHEMBL4225979)copy SMILEScopy InChI
Affinity DataEC50:  182nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460792(CHEMBL4228412)copy SMILEScopy InChI
Affinity DataEC50:  184nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50381995(CHEMBL2022369)copy SMILEScopy InChI
Affinity DataEC50:  193nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460783(CHEMBL4229135)copy SMILEScopy InChI
Affinity DataEC50:  203nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460782(CHEMBL4225385)copy SMILEScopy InChI
Affinity DataEC50:  208nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382008(CHEMBL2023294)copy SMILEScopy InChI
Affinity DataEC50:  234nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460771(CHEMBL4226704)copy SMILEScopy InChI
Affinity DataEC50:  245nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460774(CHEMBL4226494)copy SMILEScopy InChI
Affinity DataEC50:  250nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382018(CHEMBL2022377)copy SMILEScopy InChI
Affinity DataEC50:  285nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460786(CHEMBL4227557)copy SMILEScopy InChI
Affinity DataEC50:  289nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382002(CHEMBL2022121)copy SMILEScopy InChI
Affinity DataEC50:  327nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460788(CHEMBL4226969)copy SMILEScopy InChI
Affinity DataEC50:  356nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460779(CHEMBL4228135)copy SMILEScopy InChI
Affinity DataEC50:  370nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50460775(CHEMBL4226657)copy SMILEScopy InChI
Affinity DataEC50:  376nMAssay Description:Inhibition of Aurora B in human HCT116 cells assessed as reduction in phosphorylation of Histone H3 at Ser10 residue incubated for 1 hr by Hoechst 33...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K35X91PubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382013(CHEMBL2022370)copy SMILEScopy InChI
Affinity DataEC50:  388nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382010(CHEMBL2023297)copy SMILEScopy InChI
Affinity DataEC50:  389nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382019(CHEMBL2022709)copy SMILEScopy InChI
Affinity DataEC50:  402nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
TargetAurora kinase B(Homo sapiens (Human))
Ambit Biosciences Corporation

Curated by ChEMBL
LigandPNGBDBM50382015(CHEMBL2022372)copy SMILEScopy InChI
Affinity DataEC50:  412nMAssay Description:Inhibition of aurora B kinase in human HCT116 cells assessed as inhibition of histone H3 phosphorylation incubated for 1 hr by Hoechst 33342 staining...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34ZGDPubMed
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