TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 2.80nM EC50: 0.940nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 1nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 8.80nM EC50: 1.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 170nM EC50: 2.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 14nM EC50: 2.5nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 1.90nM EC50: 3nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 1.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 3nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 3.60nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 5.20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 8.30nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 20nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 39nM EC50: >3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 40nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 170nM EC50: <3.90nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 4nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 16nM EC50: 4.40nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 7nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 9nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 11nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 12.6nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 15nM EC50: 15nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 15nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 11nM EC50: 16nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 16nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 18nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 3.5nM EC50: 19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 3.5nM EC50: 19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 22nM EC50: 19nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 6.70nM EC50: 20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 120nM EC50: 20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 280nM EC50: 20nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 7.20nM EC50: 21nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 21nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 28nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 18nM EC50: 31nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 25nM EC50: 32nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 32nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 14nM EC50: 36nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataEC50: 36nMAssay Description:Inhibition of PAK4-mediated GEF-H1 phosphorylation at Ser810 by cell based assayMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 680nM EC50: 67.1nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 93nM EC50: 69nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 38nM EC50: 78nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 58nM EC50: 84nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 220nM EC50: 87nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 18nM EC50: 98nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 20nM EC50: 103nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 24nM EC50: 147nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 260nM EC50: 262nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PAK 4(Homo sapiens (Human))
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Agouron Pharmaceuticals, Inc.; Pfizer Inc.
US Patent
Affinity DataKi: 160nM EC50: 332nMAssay Description:The enzymatic activity of PAK4 KD was measured by its ability to catalyzed the transfer of a phosphate residue from a nucleoside triphosphate to an a...More data for this Ligand-Target Pair