Compile Data Set for Download or QSAR
Found 37 of ic50 data for polymerid = 11223,8119
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50152595(CHEMBL3780091)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Inhibition of AMPKa1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B6203PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564453(CHEMBL4794096)copy SMILES
Affinity DataIC50: 93nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564459(CHEMBL4781578)copy SMILES
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM4817(N-[2-(dimethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo...)copy SMILEScopy InChI
Affinity DataIC50: 136nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564462(CHEMBL4796639)copy SMILES
Affinity DataIC50: 139nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564448(CHEMBL4788980)copy SMILES
Affinity DataIC50: 152nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564458(CHEMBL4788376)copy SMILES
Affinity DataIC50: 164nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564457(CHEMBL4800500)copy SMILES
Affinity DataIC50: 173nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564446(CHEMBL3542344)copy SMILES
Affinity DataIC50: 180nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564461(CHEMBL4795330)copy SMILES
Affinity DataIC50: 184nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50212270(CHEMBL3952214)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of PRKKA1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14Q8PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50405896(CHEMBL5281003)copy SMILEScopy InChI
Affinity DataIC50: 202nMAssay Description:The compound was tested for alpha-adrenergic activity against Alpha-1 adrenergic receptor from rat aorta.More data for this Ligand-Target Pair
In DepthDetails
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564454(CHEMBL4792246)copy SMILES
Affinity DataIC50: 205nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564451(CHEMBL4782796)copy SMILES
Affinity DataIC50: 208nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564450(CHEMBL4786972)copy SMILES
Affinity DataIC50: 217nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564447(CHEMBL4799580)copy SMILES
Affinity DataIC50: 221nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564449(CHEMBL4779166)copy SMILES
Affinity DataIC50: 240nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM4813(N-[2-(diethylamino)ethyl]-2,4-dimethyl-5-{[(3Z)-2-...)copy SMILEScopy InChI
Affinity DataIC50: 246nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564455(CHEMBL4781062)copy SMILES
Affinity DataIC50: 296nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564452(CHEMBL4785831)copy SMILES
Affinity DataIC50: 348nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564445(CHEMBL3542333)copy SMILES
Affinity DataIC50: 393nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50405897(CHEMBL5277241)copy SMILEScopy InChI
Affinity DataIC50: 409nMAssay Description:Inhibitory activity against Neisseria gonorrhoeae dihydrofolate reductase at 10e8 MMore data for this Ligand-Target Pair
In DepthDetails
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564456(CHEMBL4799631)copy SMILES
Affinity DataIC50: 418nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50405895(CHEMBL5279971)copy SMILEScopy InChI
Affinity DataIC50: 446nMAssay Description:The compound was tested for alpha-adrenergic activity against Alpha-1 adrenergic receptor from rat aorta.More data for this Ligand-Target Pair
In DepthDetails
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM459444(US10752635, Example 4, Peak 2 | US11492354, Exampl...)copy SMILEScopy InChI
Affinity DataIC50: 643nMAssay Description:The compound was tested for beta-adrenergic activity against Beta-2 adrenergic receptor from guinea pig trachea.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50237288(CHEMBL4073198)copy SMILEScopy InChI
Affinity DataIC50: 794nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VV6PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM444543(US10662186, Compound 63 | US10988476, Compound I-6...)copy SMILEScopy InChI
Affinity DataIC50: 865nMAssay Description:Inhibition of AMPKa1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2CTJPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50564460(CHEMBL4779730)copy SMILES
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human His6-tagged AMPK alpha1 using ULight CRBtide as substrate incubated for 1 hr followed by substrate addition and measu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2348Q5WPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50384888(CHEMBL2035810)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of AMPKalpha1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9J8FPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50401152(CHEMBL2205766)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PRKAA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ412BPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50123803(CHEMBL3623375)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant AMPKalpha1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24X59MVPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM236557(US9365572, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4TNCUS Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50519662(CHEMBL4438748)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human full length AMPKalpha1 recombinant using AMARAASAAALAR as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93FGPubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50334268(CHEMBL1642655 | CHEMBL2205637 | N-(6-(1H-imidazol-...)copy SMILEScopy InChI
Affinity DataIC50: 1.38E+4nMAssay Description:Inhibition of PRKAA1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38VV6PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50560385(CHEMBL4759397)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PRKKA1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JQ14Q8PubMed
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Merck& Co.

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of AMPKA1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ88N1PubMed