Compile Data Set for Download or QSAR
Found 75 of ic50 data for polymerid = 233,3213
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50536937(CHEMBL4554200)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of mouse recombinant PARP2 by chemiluminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z03CPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27H1PK7PubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:A FlashPlate scintillation proximity assay has been used to identify inhibitors of PARP-2. PARP-2 protein (recombinant) was bound down by a PARP-2 sp...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM139658(US8894989, 37)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27720(3-(4-chlorophenyl)quinoxaline-5-carboxamide | quin...)copy SMILEScopy InChI
Affinity DataIC50: 7nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27723(3-(4-methoxyphenyl)quinoxaline-5-carboxamide | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27721(3-(4-cyanophenyl)quinoxaline-5-carboxamide | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 8nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27724(3-(4-aminophenyl)quinoxaline-5-carboxamide | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 9nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27722(3-[4-(trifluoromethyl)phenyl]quinoxaline-5-carboxa...)copy SMILEScopy InChI
Affinity DataIC50: 11nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27719(3-phenylquinoxaline-5-carboxamide | quinoxaline an...)copy SMILEScopy InChI
Affinity DataIC50: 14nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27493(2-[4-(5-methyl-1H-imidazol-4-yl)piperidin-1-yl]-1,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27494(2-[4-(pyridin-2-yl)phenyl]-1,3-diazatricyclo[6.3.1...)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27498(10-amino-3-azatricyclo[7.3.1.0^{5,13}]trideca-1(13...)copy SMILEScopy InChI
Affinity DataIC50: 32nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27497(2-(dimethylamino)-N-(6-oxo-5,6-dihydrophenanthridi...)copy SMILEScopy InChI
Affinity DataIC50: 62nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27713(1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)buty...)copy SMILEScopy InChI
Affinity DataIC50: 70nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27714(5-fluoro-1-[4-(4-phenyl-1,2,3,6-tetrahydropyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 83nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27718(2-(3-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)propyl)...)copy SMILEScopy InChI
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27717(4-{4-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 84nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27707(4-{1-[3-(8-chloro-4-oxo-3,4-dihydroquinazolin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 87nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27716(4-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 90nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341859(2-(4-chlorophenyl)quinoxaline-5-carboxamide | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438603(CHEMBL2414044)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438601(CHEMBL2414046)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27709(2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahydropyridin...)copy SMILEScopy InChI
Affinity DataIC50: 167nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438605(CHEMBL2414042)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27499(1,11b-dihydro-[2H]benzopyrano[4,3,2-de]isoquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 186nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438600(CHEMBL2414048)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27711(2-{3-[4-(4-chlorophenyl)piperazin-1-yl]propyl}-3,4...)copy SMILEScopy InChI
Affinity DataIC50: 300nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27500(5,6-dihydrophenanthridin-6-one | 5H-Phenanthridin-...)copy SMILEScopy InChI
Affinity DataIC50: 331nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27501(1,5-dihydroxyisoquinoline | CHEMBL338314 | ISQ | i...)copy SMILEScopy InChI
Affinity DataIC50: 447nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438604(CHEMBL2414043)copy SMILEScopy InChI
Affinity DataIC50: 480nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341860(8-chloro-2-(4-(4-(4-fluorophenyl)-5,6-dihydropyrid...)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27708(8-chloro-2-{3-[4-(4-fluorophenyl)-1,2,3,6-tetrahyd...)copy SMILEScopy InChI
Affinity DataIC50: 500nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341856(5-(Carboxymethylamino)isoquinolin-1-one | CHEMBL17...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27705(2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)prop...)copy SMILEScopy InChI
Affinity DataIC50: 608nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27706(8-chloro-2-[3-(4-phenyl-1,2,3,6-tetrahydropyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 610nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27710(5-Chloro-2-[3-(4-phenyl-3,6-dihydro-2H-pyridin-1-y...)copy SMILEScopy InChI
Affinity DataIC50: 630nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27712(5-chloro-2-methyl-3,4-dihydroquinazolin-4-one | CH...)copy SMILEScopy InChI
Affinity DataIC50: 660nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2610XPZPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438602(CHEMBL2414045)copy SMILEScopy InChI
Affinity DataIC50: 730nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50438599(CHEMBL2414051)copy SMILEScopy InChI
Affinity DataIC50: 830nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27503(5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27503(5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27503(5-AIQ | 5-amino-1,2-dihydroisoquinolin-1-one | 5-a...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of mouse PARP-2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP047DPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341867(5-(4-Iodobenzamido)isoquinolin-1-one | CHEMBL17670...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341861(5-Benzamidoisoquinolin-1-one | CHEMBL1767054)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM39220((1-oxidanylidene-2H-isoquinolin-5-yl) benzoate | (...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341861(5-Benzamidoisoquinolin-1-one | CHEMBL1767054)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341857(5-Amino-2-(2-carboxyethyl)isoquinolin-1-one | CHEM...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM50341863(5-(4-Nitrobenzamido)isoquinolin-1-one | CHEMBL1767...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant full length mouse PARP-2 after 10 mins using [3H]NAD+ by solution-phase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24B31NCPubMed
TargetPoly [ADP-ribose] polymerase 2(Mus musculus (Mouse))
Nirma University

Curated by ChEMBL
LigandPNGBDBM27502(3,4-dihydro-5-(4-(1-piperidinyl)butoxy)-1(2H)-isoq...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+3nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61HKGPubMed
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