Compile Data Set for Download or QSAR
Found 57 of ic50 data for polymerid = 2890,50006501
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50091786(4-[4-(3,4-Difluoro-phenyl)-thiazol-2-yl]-N-{4-[2-(...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro functional efficacy as increased cAMP in chinese hamster ovary (CHO) cells expressing human beta-3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F5MPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092646(CHEMBL331744 | N-{4-[2-(2-Hydroxy-2-pyridin-3-yl-e...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Binding affinity was evaluated on chinese hamster ovary (CHO) cells expressing the cloned human beta-3 adrenergic receptor in the presence of [125I]-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F5MPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50092645((R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)...)copy SMILEScopy InChI
Affinity DataIC50: 46nMAssay Description:In vitro functional efficacy as increased cAMP in chinese hamster ovary (CHO) cells expressing human beta-3 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2057F5MPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50076960(4-[4-(3-Cyclopentyl-propyl)-5-oxo-4,5-dihydro-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibitory activity against cloned human Beta-3 adrenergic receptor in the presence of [125I]-iodocyanopindolol expressed in CHO cells by receptor bi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RB73RNPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328307(CHEMBL1258825 | N-(3-(2-hydroxy-3-(1-(5-phenylthie...)copy SMILEScopy InChI
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1DNRPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328327(1-(4-(hydroxymethyl)phenoxy)-3-(1-(5-phenylthieno[...)copy SMILEScopy InChI
Affinity DataIC50: 162nMAssay Description:Antagonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1DNRPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328306(3-(2-hydroxy-3-(1-(5-phenylthieno[2,3-d]pyrimidin-...)copy SMILEScopy InChI
Affinity DataIC50: 402nMAssay Description:Antagonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1DNRPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50275222(1-(1-Benzyl-1,2,3,4-tetrahydroquinolin-6-yloxy)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMAssay Description:Displacement of [125I]iodocynopindolol from human adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z3BPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50274875(1-(1-Benzyl-1,2,3,4-tetrahydroquinolin-6-yloxy)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 590nMAssay Description:Displacement of [125I]iodocynopindolol from human adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z3BPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50403975(CHEMBL315772)copy SMILEScopy InChI
Affinity DataIC50: 871nMAssay Description:Binding affinity against Alpha-3A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M384XPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421590(CHEMBL331188)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against Alpha-3A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M384XPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421589(CHEMBL331077)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity against Alpha-3A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M384XPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50275223(1-(1-Benzyl-1,2,3,4-tetrahydroquinolin-6-yloxy)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+3nMAssay Description:Displacement of [125I]iodocynopindolol from human adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z3BPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318991(2-((1-(2-hydroxy-3-(2-isopropyl-5-methylphenoxy)pr...)copy SMILEScopy InChI
Affinity DataIC50: 1.47E+3nMAssay Description:Antagonist activity at human adrenergic beta3 receptor expressed in CHOK1 cells assessed as inhibition of cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D21XSWPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50275224(1-(1-Benzyl-1,2,3,4-tetrahydroquinolin-6-yloxy)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.76E+3nMAssay Description:Displacement of [125I]iodocynopindolol from human adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z3BPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50146360(CHEMBL328573 | Dimethyl-[(2S,3aR)-1-(2,3,3a,8-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 1.86E+3nMAssay Description:Binding affinity against Alpha-3A adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26M384XPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244809((2R)-2-[3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)copy SMILEScopy InChI
Affinity DataIC50: 4.86E+3nMAssay Description:Displacement of radioligand from adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BC3ZC5PubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50311095(CHEMBL1079045 | N-(4-(2-amino-2-methylpropyl)pheny...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of human adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V124X7PubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484071((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...)copy SMILES
Affinity DataIC50: 7.00E+3nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50328312(1-(4-ethylphenoxy)-3-(1-(5-phenylthieno[2,3-d]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 8.06E+3nMAssay Description:Antagonist activity at human recombinant adrenergic beta3 receptor expressed in CHO cells assessed as inhibition of isoproterenol-induced cyclic AMP ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1DNRPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50304075(3-(5-(4-tert-butylphenyl)-3-((dimethylamino)methyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of beta3 adrenergic receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QZ2B14PubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484061((2S)-1-(3-(1- fluoroethylsulfonyl) phenoxy)-3-((R)...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484073((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...)copy SMILES
Affinity DataIC50: 1.12E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484058((S)-1-((S)-8-(4'- (aminomethyl)-5- methoxybiphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484059((S)-1-((S)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484060((S)-1-((S)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484076(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)copy SMILES
Affinity DataIC50: 1.73E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484050((S)-1-((S)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.73E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484051((S)-1-((R)-8-(4'- (aminomethyl)-4- fluorobiphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484048((S)-1-(3-(cyclopropyl- sulfonyl)phenoxy)- 3-((R)-8...)copy SMILEScopy InChI
Affinity DataIC50: 1.75E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484073((S)-1-((R)-8-(1H- pyrrolo[3,2-b]pyridin-6- ylsulfo...)copy SMILES
Affinity DataIC50: 1.78E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484057((S)-1-((S)-8-(4'- (aminomethyl)-6- methoxybiphenyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.79E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484066((S)-1-((S)-8-(4'- ((butylamino)methyl) biphenyl-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.84E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484047((S)-1-(3-(1- (hydroxymethyl) cyclopropylsulfonyl) ...)copy SMILEScopy InChI
Affinity DataIC50: 1.88E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484070((S)-1-(3-(1- (hydroxymethyl) cyclopropylsulfonyl) ...)copy SMILEScopy InChI
Affinity DataIC50: 2.04E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484063((S)-1-(3-(1- (hydroxymelhyl) cyclopropylsulfonyl) ...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484049((S)-1-((R)-8-(4'- (aminomethyl)-4- ethoxybiphenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 2.11E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484075(1-ethyl-8-fluoro-3-((R)- 3-((S)-2-hydroxy-3-(3- (m...)copy SMILEScopy InChI
Affinity DataIC50: 2.18E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484053((S)-1-((S)-8-(4'-(2- aminoethyl)biphenyl-3- ylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 2.24E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484052((S)-1-((R)-8-(4'-(1- aminocyclopropyl)-6- methoxyb...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484045((S)-1-(3-(2- hydroxyethylsulfonyl) phenoxy)-3-(R)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484054((S)-1-((S)-8-(4'-(2- aminoethyl)biphenyl-3- ylsulf...)copy SMILEScopy InChI
Affinity DataIC50: 2.62E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484069(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484065((S)-l-(3-(l- (hydroxymethyl) cyclopropylsulfonyl) ...)copy SMILEScopy InChI
Affinity DataIC50: 2.78E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484055((S)-1-((R)-8-(4'-(1- aminocyclopropyl)-6- fluorobi...)copy SMILEScopy InChI
Affinity DataIC50: 2.84E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484077(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 2.89E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484078(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)copy SMILEScopy InChI
Affinity DataIC50: 2.95E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50318666((1R,3S)-5',7-Dichloro-6-fluoro-3-methyl-2,3,4,9-te...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Binding affinity to human recombinant adrenergic beta3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SB45ZBPubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484079(1-ethyl-8-fluoro-3-((R)- 3-((S)-2-hydroxy-3-(3- (i...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM484062((S)-1-((S)-8-(4'-((tert- butylamino(methyl) biphen...)copy SMILEScopy InChI
Affinity DataIC50: 3.17E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D221QMUS Patent
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