Compile Data Set for Download or QSAR
Found 8 of ic50 data for polymerid = 4979
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84869(Swainsonine derivative, 4)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84868(Swainsonine derivative, 3)copy SMILEScopy InChI
Affinity DataKi:  2.70nM ΔG°:  -48.9kJ/mole IC50: 29nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84867(Swainsonine derivative, 2)copy SMILEScopy InChI
Affinity DataKi:  2.80nM ΔG°:  -48.8kJ/mole IC50: 30nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM50168995((-)-swainsonine | (1S,2R,8R,8aR)-Octahydro-indoliz...)copy SMILEScopy InChI
Affinity DataKi:  3nM ΔG°:  -48.6kJ/mole IC50: 37nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84871(Swainsonine derivative, 6)copy SMILEScopy InChI
Affinity DataIC50: 44nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84872(Swainsonine derivative, 7)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84870(Swainsonine derivative, 5)copy SMILEScopy InChI
Affinity DataIC50: 250nMpH: 5.75 T: 2°CAssay Description:Inhibition of dGMII was measured at pH 5.75. Determination of the IC50 values (concentrations of inhibitor at which 50% of activity remains) was car...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8RRMPubMed
TargetAlpha-mannosidase 2(Drosophila melanogaster (Fruit fly))
University of Toronto

LigandPNGBDBM84468(Mannostatin analogue, 4b | Meso-aminocyclopentitet...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:The rate of hydrolysis catalyzed by drosophila golgi alpha-mannosidase II (dGMII)and in the presence of different concentration of inhibitor was meas...More data for this Ligand-Target Pair