Compile Data Set for Download or QSAR
Found 17 of ic50 data for polymerid = 50000302
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407385(CHEMBL5284450)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50100341((2E,4E,6E,12E)-(8R,10S,14R)-8,10,12,14-Tetramethyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407383(CHEMBL5278618)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Functional potency against Tachykinin receptor 2 (NK2) in rabbit pulmonary artery assayMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407376(CHEMBL5284579)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Negative log concentration of antagonist was determined on 5-hydroxytryptamine 2B receptor of Rat stomach fundusMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50407377(CHEMBL5270975)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Negative log concentration of antagonist on 5-hydroxytryptamine 2A receptor in rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50221658(CHEMBL110491)copy SMILEScopy InChI
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50221662(CHEMBL320658)copy SMILEScopy InChI
Affinity DataIC50: 2.77E+4nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50214969(1,3,6-Trihydroxy-7-methoxy-2,8-bis-(3-methyl-but-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50221661(CHEMBL110445)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122309(((3S,4R)-1,1-Difluoro-3-hexadecanoylamino-4-hydrox...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+5nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50221660(CHEMBL109045)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50221659(CHEMBL107844)copy SMILEScopy InChI
Affinity DataIC50: 2.92E+5nMAssay Description:Inhibitory activity against NSMase (neutral sphingomyelinase)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49SZ9PubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122310(((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122310(((2R,3R,4R)-1,1-Difluoro-3-hexadecanoylamino-2,4-d...)copy SMILEScopy InChI
Affinity DataIC50: 3.77E+5nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed
TargetSphingomyelin phosphodiesterase 2(Homo sapiens (Human))TBA
LigandPNGBDBM50122311(CHEMBL77022 | {2-[((E)-(3S,4R)-1,1-Difluoro-4-hydr...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibitory activity of the compound against neutral sphingomyelinase (N-SMase) from bovine brain microsomesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K64HFHPubMed