Compile Data Set for Download or QSAR
Found 54 of ic50 data for polymerid = 50000311
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279436(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106179(CHEMBL125327 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279740(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279471(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106169(CHEMBL338973 | Enantiomer-4-(3-Butyl-[1,2,4]oxadia...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279454(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 9.5nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106167(CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106167(CHEMBL125000 | Enantiomer-4-(3-Cyclopropylmethyl-[...)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279703(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106178(4-(3-Butyl-[1,2,4]oxadiazol-5-yl)-N-(3,3-dimethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106168(CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279453(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106168(CHEMBL124448 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 27nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50061218((E)-3-(2,4-Dichloro-phenyl)-N-((R)-1-methyl-2-oxo-...)copy SMILEScopy InChI
Affinity DataIC50: 31nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106176(CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106176(CHEMBL340681 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Bindind affinity values obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279717(1-(2,3-dihydro-6-chlorochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50099582((3R,4S)N-[3-Hydroxy-2,2-dimethyl-6-(4,4,4-trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN16X5PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106182(CHEMBL123085 | N-(3,3-Dimethyl-butyl)-4-(3-phenyl-...)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50117913((E)-1-((5-(4-chlorophenyl)furan-2-yl)methyleneamin...)copy SMILEScopy InChI
Affinity DataIC50: 240nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106166(CHEMBL122341 | N-(3,3-Dimethyl-butyl)-4-hexyloxy-b...)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106177(CHEMBL431682 | N-(3,3-Dimethyl-butyl)-4-indol-1-yl...)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279456(1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279719(1-(2,3-dihydro-6-amidecarboxylchromen-4-ylideneami...)copy SMILEScopy InChI
Affinity DataIC50: 330nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106184(CHEMBL121751 | N-(3,3-Dimethyl-cyclopentyl)-4-hexy...)copy SMILEScopy InChI
Affinity DataIC50: 360nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106180(CHEMBL124595 | N-(3,3-Dimethyl-cyclohexylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 370nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106181(Biphenyl-4-carboxylic acid (3,3-dimethyl-butyl)-am...)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106164(CHEMBL123569 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106164(CHEMBL123569 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279700(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106175(CHEMBL121750 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from whole rat brain Nicotinic acetylcholine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106175(CHEMBL121750 | Enantiomer-N-(2,2-Dimethyl-cyclopen...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279741(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279739(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279455(1-(6-butoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279702(1-(2,3-dihydro-6-propoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106174(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106165((3-tert-Butyl-pyrrolidin-1-yl)-(4-hexyloxy-phenyl)...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106174(CHEMBL332297 | N-(2,2-Dimethyl-cyclohexylmethyl)-4...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Bindind affinity value obtained by measuring the displacement of radioligand [3H]-(-)-cytisine from a preparation of whole rat brainMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106170(CHEMBL122865 | N-(2-Diethylamino-ethyl)-4-hexyloxy...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106183(1-(4-(Hexyloxy)phenyl)-3-(piperidin-1-yl)propan-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106171(CHEMBL122637 | Diethyl-{2-[4-(1,1,3,3-tetramethyl-...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106227((3R,4S)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of guinea pig Iks potassium channel expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN16X5PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106173(CHEMBL341368 | N,N-Diethyl-2-[4-(1,1,3,3-tetrameth...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279433(1-(2,3-dihydro-6-hydroxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50099567((3S,4R)-Ethanesulfonic acid (6-cyano-3-hydroxy-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Invitro evaluation against RXR-alpha in CV-1 cells by cotransfection assay was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN16X5PubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279701(1-(6-ethoxy-2,3-dihydrochromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279435(1-(2,3-dihydro-6-methylchromen-4-ylideneamino)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50279738(1-(2,3-dihydro-6-methoxychromen-4-ylideneamino)-3-...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of KVLQT1/minK in guinea pig ventricular myocytes assessed as blockade of slow delayed rectifier potassium current by whole cell patch-cla...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6BQKPubMed
TargetPotassium voltage-gated channel subfamily KQT member 1(Cavia porcellus)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50106172(CHEMBL340222 | N-(2,2-Dimethyl-cyclopentyl)-4-hexy...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Molar concentration required to inhibit 50% of the activating delayed-rectifier K+ current in isolated guinea pig ventricularmyocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G1604CPubMed
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