Compile Data Set for Download or QSAR
Found 36 of ic50 data for polymerid = 50004179
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319716((3S,4R)-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of CDC42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12MDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50391237(CHEMBL5290216)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:In vitro inhibition of angiotensin I converting enzyme in rabbit lung with hippuryl-histidyl-leucine as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319634(CHEMBL1084892 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300554(((2S,3R,4S,5S)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319633(2-amino-N-(7-chloro-1-oxo-1,2-dihydroisoquinolin-6...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308894(3-[3-(3-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308897(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308862(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308861(3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(4-dimethyla...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308898(3-[3-(4-Amido-phenyl)-ureidomethyl]-N-(1,2,3,4-tet...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308866(3-Chloro-N-[3-(4-dimethylaminomethyl-phenylcarbamo...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308875(3,4-Dimethoxy-N-[3-(2-methyl-1,2,3,4-tetrahydro-is...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308876(3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308900(3,4-Dimethoxy-N-[3-(3-piperidin-3-yl-propionylamin...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308877(3,4-Dimethoxy-N-[3-(2-piperidin-4-yl-ethylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308872(3,4-Dimethoxy-N-[3-(2-piperidin-3-yl-ethylcarbamoy...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50308871(CHEMBL599792 | N-[3-(4-Dimethylaminomethyl-phenylc...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Cdc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V125RDPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319632(CHEMBL1084890 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300547(2,3,9,10-Tetrahydroxy-5,6-dihydro-isoquino[3,2-a]i...)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324673(CHEMBL1222039 | Secramine B)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 after 3 mins in presence of 4 mM Mg2+ chelator EDTAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60BRPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14027(5-(1,4-diazepan-1-ylsulfonyl)isoquinoline | 5-(1,4...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319637(2-(benzylamino)-N-(7-chloro-1-oxo-1,2-dihydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319636(CHEMBL1084107 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM14029((R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXA...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50319635(CHEMBL1084106 | N-(7-chloro-1-oxo-1,2-dihydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of CDc42More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21N819ZPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50324672(CHEMBL1222038 | Secramine A)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of GEF-independent nucleotide exchange activity of prenylated Cdc42 after 3 mins in presence of 4 mM Mg2+ chelator EDTAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B60BRPubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300551(2,3,7,8-Tetrahydroxy-5-methyl-benzo[c]phenanthridi...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300548(3,4,10,11-Tetrahydroxy-8-methyl-isoquino[3,2-a]iso...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM25525(24-methyl-5,7,18,20-tetraoxa-24-azahexacyclo[11.11...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300552(2,3-Dihydroxy-7,8-dimethoxy-5-methyl-benzo[c]phena...)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300550(3-(3,4-Dihydroxy-phenyl)-6,7-dimethoxy-1-methyl-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300549(2,3-Dihydroxy-9,10-dimethoxy-5,6-dihydro-isoquino[...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300545(CHEMBL573174 | tetrahydroxycanadine hydrochloride)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM50300546(6,7-Dimethoxy-1-methyl-3-naphthalen-2-yl-isoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed
TargetCell division control protein 42 homolog(Homo sapiens (Human))
Boehringer-Ingelheim Pharmaceuticals, Inc.

Curated by ChEMBL
LigandPNGBDBM25524(17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyc...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Cdc42 GTPase activity assessed as incorporation of BODIPY-GTP after 40 mins by nucleotide binding competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27P8ZF4PubMed