Compile Data Set for Download or QSAR
Found 13 of ic50 data for polymerid = 50006114,50006385
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434850(CHEMBL2387397)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434850(CHEMBL2387397)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434849(CHEMBL2385105 | US9040518, 6)copy SMILEScopy InChI
Affinity DataIC50: 0.5nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434846(CHEMBL2387399 | US9040518, 35)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434849(CHEMBL2385105 | US9040518, 6)copy SMILEScopy InChI
Affinity DataIC50: 0.900nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM47370(BDBM50434858 | US9040518, 26)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM47370(BDBM50434858 | US9040518, 26)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50434846(CHEMBL2387399 | US9040518, 35)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50134411((7R,9R)-7-Butyl-7-ethyl-2,3-dimethoxy-9-phenyl-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of mouse ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Rattus norvegicus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50134411((7R,9R)-7-Butyl-7-ethyl-2,3-dimethoxy-9-phenyl-6,7...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of rat ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC91D6PubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50459098(CHEMBL4205214)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56NCHPubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50459099(CHEMBL4202981)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56NCHPubMed
TargetIleal sodium/bile acid cotransporter(Mus musculus)
GlaxoSmithKline Research& Development

Curated by ChEMBL
LigandPNGBDBM50459096(CHEMBL4217797)copy SMILEScopy InChI
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of mouse IBAT expressed in COS cells assessed as reduction in [3H]taurocholic acid uptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B56NCHPubMed