Compile Data Set for Download or QSAR
Found 1682 of ic50 data for polymerid = 8880
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252685(US9458176, 82)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252846(US9458176, 243)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252686(US9458176, 83)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252847(US9458176, 244)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252770(US9458176, 167)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252612(US9458176, 9)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252837(US9458176, 234)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332963(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332966(7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332964(4-(3-(2-ethyl-6-methylpyridin-4-yl)phenyl)-7-methy...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332965(4-(3-(2-cyclopropyl-6-methylpyridin-4-yl)phenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252836(US9458176, 233)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332962(7-methyl-4-(3-(pyridin-3-yl)phenyl)-8-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252834(US9458176, 231)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252804(US9458176, 201)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252845(US9458176, 242)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252642(US9458176, 39)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252619(US9458176, 16)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252638(US9458176, 35)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252637(US9458176, 34)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252635(US9458176, 32)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252839(US9458176, 236)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50062522((1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-y...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252844(US9458176, 241)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252622(US9458176, 19)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332967(8-chloro-4-(3-(pyridin-4-yl)phenyl)-1H-benzo[b][1,...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332963(4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332962(7-methyl-4-(3-(pyridin-3-yl)phenyl)-8-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252756(US9458176, 153)copy SMILEScopy InChI
Affinity DataIC50: 3nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252701(US9458176, 98)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252628(US9458176, 25)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252623(US9458176, 20)copy SMILEScopy InChI
Affinity DataIC50: 3.40nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50376408(CHEMBL409928)copy SMILEScopy InChI
Affinity DataIC50: 3.49nMAssay Description:Displacement of [3H]-MGS0008 from mGluR2 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PG1SMMPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252630(US9458176, 27)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252798(US9458176, 195)copy SMILEScopy InChI
Affinity DataIC50: 3.70nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252620(US9458176, 17)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252681(US9458176, 78)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252632(US9458176, 29)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252799(US9458176, 196)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252828(US9458176, 225)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM252807(US9458176, 204)copy SMILEScopy InChI
Affinity DataIC50: 4nMT: 2°CAssay Description:The frozen cell membrane fraction prepared as described above was thawed before use, and the resultant was diluted with a buffer for a binding assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PK0F3DUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM213143(US9278960, 8-50 | US9636337, 8-50)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PC34H4US Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM213143(US9278960, 8-50 | US9636337, 8-50)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:The utility of the compounds in accordance with the present invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191TKUS Patent
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50376487(CHEMBL261050)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]LY354740 from rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75H7DPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332965(4-(3-(2-cyclopropyl-6-methylpyridin-4-yl)phenyl)-7...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332964(4-(3-(2-ethyl-6-methylpyridin-4-yl)phenyl)-7-methy...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332970(7-methyl-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(tri...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Antagonist activity at recombinant rat mGluR2 expressed in forskolin-stimulated CHO cells assessed as inhibition of (1S,3R)-ACPD induced cAMP product...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332966(7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332972(7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluorome...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Eisai R&D Management Co., Ltd.

US Patent
LigandPNGBDBM50332971(4-(3-(2-isopropylpyridin-4-yl)phenyl)-7-methyl-8-(...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Partial displacement of [3H]LY354740 from recombinant rat mGluR2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X63N6RPubMed
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