Compile Data Set for Download or QSAR
Found 36 of ic50 data for polymerid = 9627
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM200723(US9233086, 10L)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92ZSPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM200712(US9233086, 10A)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92ZSPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM200722(US9233086, 10K)copy SMILEScopy InChI
Affinity DataIC50: 4.5nMAssay Description:Inhibition of MLL1 binding to N-terminal His-tagged WRD5 23 deletion mutant (24 to 334 residues) (unknown origin) expressed in Escherichia coli Roset...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92ZSPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601694(CHEMBL5183439)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85D61PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50574672(CHEMBL4861912)copy SMILES
Affinity DataIC50: 174nMAssay Description:Inhibition of MLL1 (unknown origin)-mediated H3K4 methylation using histone H3 and SAM as substrate incubated for 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38XCRPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50601692(CHEMBL5172154)copy SMILES
Affinity DataIC50: 190nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85D61PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164787(CHEMBL3798088)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of SUMO-His-tagged MLL1 activity (unknown origin) expressed in Escherichia coli BL21(DE3) pLysS cells using histone H3 as substrate by sci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VT1V0CPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50164787(CHEMBL3798088)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant SUMO-tagged MLL1 (unknown origin) by histone methyl transferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F76G3GPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50581147(CHEMBL5094242)copy SMILES
Affinity DataIC50: 780nMAssay Description:Inhibition of MLL1 (unknown origin) histamine methyltransferase activity assessed as inhibition of H3K4 methylation incubated for 30 mins by Alphascr...More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B92X1PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530867(CHEMBL4472654)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant MLL1 using [3H]S-adenosyl-methionine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QB2PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50530867(CHEMBL4472654)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant MLL1 using [3H]S-adenosyl-methionine as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2C53QB2PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)copy SMILEScopy InChI
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MLL (unknown origin) by HMT assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23411(5,6,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.92E+3nMAssay Description:Inhibition of MLL1 (unknown origin) preincubated for 15 mins followed by addition of substrate measured after 1 hr by AlphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0ZG9PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594525(CHEMBL5189434)copy SMILES
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594527(CHEMBL5177921)copy SMILES
Affinity DataIC50: 4.90E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594520(CHEMBL5194845)copy SMILES
Affinity DataIC50: 7.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594530(CHEMBL5181110)copy SMILES
Affinity DataIC50: 7.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594528(CHEMBL5178563)copy SMILES
Affinity DataIC50: 1.50E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50063670(CHEMBL3397332)copy SMILES
Affinity DataIC50: 1.85E+4nMAssay Description:Inhibition of MLL (unknown origin) by HMT assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CSSPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50606100(CHEMBL5173004)copy SMILES
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2DNQPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50572749(CHEMBL4854710)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MLLI (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by HTRF metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43QPPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594529(CHEMBL5201158)copy SMILES
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594521(CHEMBL5193964)copy SMILES
Affinity DataIC50: 4.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594523(CHEMBL5182454)copy SMILES
Affinity DataIC50: 4.30E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594531(CHEMBL5198555)copy SMILES
Affinity DataIC50: 4.60E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594526(CHEMBL5185919)copy SMILES
Affinity DataIC50: 5.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594533(CHEMBL5175295)copy SMILES
Affinity DataIC50: 7.40E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594535(CHEMBL5191621)copy SMILES
Affinity DataIC50: 7.60E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50051117(CHEMBL3318285)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLL1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J9681QPubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50400778(CHEMBL2204995)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLL1 using core histone as substrate preincubated for 10 mins followed by addition of [3H]SAM and incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G60PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594536(CHEMBL5182357)copy SMILES
Affinity DataIC50: 1.14E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594534(CHEMBL5206543)copy SMILES
Affinity DataIC50: 1.36E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50031317(CHEMBL3358015)copy SMILES
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibition of MLL1 (unknown origin) incubated for 15 mins before addition of biotinylated peptide H3 (1 to 21) and SAM by methylation assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JD4ZD6PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594532(CHEMBL5169812)copy SMILES
Affinity DataIC50: 1.53E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594522(CHEMBL5172213)copy SMILES
Affinity DataIC50: 4.95E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed
TargetHistone-lysine N-methyltransferase 2A(Homo sapiens (Human))
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50594524(CHEMBL5173950)copy SMILES
Affinity DataIC50: 8.27E+5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2930Z58PubMed