Compile Data Set for Download or QSAR
Found 2104 of ki data for polymerid = 1357
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50260646(CHEMBL4096251)copy SMILEScopy InChI
Affinity DataKi:  0.0200nMAssay Description:Inhibition of human F11a using peptide substrate by spectrophotometryMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50230326(CHEMBL4060950)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QPSPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50230326(CHEMBL4060950)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Inhibition of human coagulation factor 11a using pyroGlu-Pro-Arg-pNA as substrate after 10 to 120 mins at 37 degC by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8V31PubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241371(US9409908, 3 | US9951071, Example 3)copy SMILEScopy InChI
Affinity DataKi:  0.0300nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357210(US10214512, Example 151-a)copy SMILES
Affinity DataKi:  0.0400nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50096792(CHEMBL3580759)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Inhibition of human coagulation factor 11a using p-nitroaniline as substrate assessed as substrate hydrolysis by spectrophotometryMore data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241399(US9409908, 31 | US9951071, Example 31)copy SMILEScopy InChI
Affinity DataKi:  0.0400nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241503(US9409908, 135 | US9951071, Example 135)copy SMILES
Affinity DataKi:  0.0500nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241552(US9409908, 184 | US9951071, Example 184)copy SMILEScopy InChI
Affinity DataKi: <0.0500nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241436(US9409908, 68 | US9951071, Example 68)copy SMILEScopy InChI
Affinity DataKi:  0.0500nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241567(US9409908, 199 | US9951071, Example 199)copy SMILES
Affinity DataKi: <0.0500nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241566(US9409908, 198 | US9951071, Example 198)copy SMILEScopy InChI
Affinity DataKi: <0.0500nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50269207(CHEMBL4097522)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QPSPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241451(US9409908, 83 | US9951071, Example 83)copy SMILES
Affinity DataKi:  0.0600nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241400(US9409908, 32 | US9951071, Example 32)copy SMILEScopy InChI
Affinity DataKi:  0.0600nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50582801(CHEMBL5076656)copy SMILES
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20005Z7PubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50250493(CHEMBL4068445)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50269199(CHEMBL4083769)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Inhibition of human Factor XIa using S-2366 as chromogenic substrate after 60 mins by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5QPSPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241583(US9409908, 215 | US9951071, Example 215)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241421(US9409908, 53 | US9951071, Example 53)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50011242(CHEMBL3260339)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Inhibition of human coagulation factor 11a after 20 to 180 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67JFRPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357161(US10214512, Example 117)copy SMILES
Affinity DataKi:  0.0800nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241422(US9409908, 54 | US9951071, Example 54)copy SMILEScopy InChI
Affinity DataKi:  0.0800nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241468(US9409908, 100 | US9951071, Example 100)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241472(US9409908, 104 | US9951071, Example 104)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357214(US10214512, Example 152-a)copy SMILES
Affinity DataKi:  0.0900nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357017((S) 5-(5-chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(25-...)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241394(US9409908, 26 | US9951071, Example 26)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241404(US9409908, 36 | US9951071, Example 36)copy SMILEScopy InChI
Affinity DataKi:  0.0900nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM50250492(CHEMBL4097304)copy SMILEScopy InChI
Affinity DataKi:  0.0980nMAssay Description:Inhibition of human factor 11a using pyro-Glu-Pro-Arg-pNA as substrate at 37 degC after 10 to 120 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2K64MHNPubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247414(US10336754, Example 368 | US11053247, Example 368 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ4325US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357026(5-(5-Chloro-2-(1H-tetrazol-1-yl)phenyl)-2-(24-((me...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247416(US10336754, Example 369 | US11053247, Example 369 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ4325US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247417(US10336754, Example 371 | US11053247, Example 371 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ4325US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247417(US10336754, Example 371 | US11053247, Example 371 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ4325US Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241549(US9409908, 181 | US9951071, Example 181)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247414(US10336754, Example 368 | US11053247, Example 368 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D6FUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247414(US10336754, Example 368 | US11053247, Example 368 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D6FUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247416(US10336754, Example 369 | US11053247, Example 369 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D6FUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247417(US10336754, Example 371 | US11053247, Example 371 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D6FUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247417(US10336754, Example 371 | US11053247, Example 371 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2474D6FUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM241393(US9409908, 25 | US9951071, Example 25)copy SMILEScopy InChI
Affinity DataKi:  0.100nMAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R78HKQUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM357188(US10214512, Example 143-b)copy SMILES
Affinity DataKi:  0.100nMAssay Description:The effectiveness of a compound of the present invention as an inhibitor of Coagulation Factor XIa can be determined using a relevant purified serine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GGNUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247414(US10336754, Example 368 | US11053247, Example 368 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X27VBUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247414(US10336754, Example 368 | US11053247, Example 368 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X27VBUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247416(US10336754, Example 369 | US11053247, Example 369 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X27VBUS Patent
TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb Company, Research and Development, 350 Carter Road, Hopewell, NJ 08540 United States.

Curated by ChEMBL
LigandPNGBDBM247417(US10336754, Example 371 | US11053247, Example 371 ...)copy SMILEScopy InChI
Affinity DataKi:  0.100nM ΔG°:  -59.4kJ/molepH: 7.4 T: 2°CAssay Description:Factor XIa determinations were made in 50 mM HEPES buffer at pH 7.4 containing 145 mM NaCl, 5 mM KCl, and 0.1% PEG 8000 (polyethylene glycol; JT Bake...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25X27VBUS Patent
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