Compile Data Set for Download or QSAR
Found 12 of ki data for polymerid = 1579
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50150119(CHEMBL3769414)copy SMILEScopy InChI
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068W7PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50150264(CHEMBL3769817)copy SMILEScopy InChI
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068W7PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362033(CHEMBL1939912)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362047(CHEMBL1940057)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362046(CHEMBL1940056)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362048(CHEMBL1940058)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362035(CHEMBL1939914)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362036(CHEMBL1939915)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50362043(CHEMBL1940053)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]cAMP from PDE8A1 by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862GWCPubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50150171(CHEMBL3770470)copy SMILEScopy InChI
Affinity DataKi:  3.30E+4nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068W7PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50150239(CHEMBL3769461)copy SMILEScopy InChI
Affinity DataKi:  5.40E+4nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068W7PubMed
TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Homo sapiens (Human))
Intra-Cellular Therapies, Inc.

Curated by ChEMBL
LigandPNGBDBM50150238(CHEMBL3770107)copy SMILEScopy InChI
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of recombinant full lenght human PDE8A using fluorescent labeled cAMP as substrate after 15 mins by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X068W7PubMed